Results 51 to 60 of about 163,121 (346)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The podiform chromitites in the Dagküplü and Kavad mines, Eskisehir ophiolite (NW-Turkey): Genetic implications of mineralogical and geochemical data

Geologica Acta, 2009
Mantle tectonites from Eskisehir (NW-Turkey) include high-Cr chromitites with limited variation of Cr#, ranging from 65 to 82. Mg# ratios are between 54 and 72 and chromite grains contain up to 3.71 wt% Fe2O3 and 0.30 wt% TiO2.
I. UYSAL, F. ZACCARINI, M.B. SADIKLAR, M. TARKIAN, O.A.R. THALHAMMER, G. GARUTI   +5 more
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basic Study on Distribution Behavior of Platinum Group Ions Using TPPS-[Cnmim][Tf2N] in Hydrochloric Acid Medium

Journal of MMIJ, 2017
Although solvent extraction has been used in the recovery of rare metals from urban mines, some challenges remain. For example, large amounts of organic solvent are required for Pd (II) separation owing to the slow extraction kinetics of dihexylsulfide ...
Takumi YAMANAKA, Yumi MATSUMOTO, Yuji YADA, Tsuyoshi ARAI   +3 more
doaj   +1 more source

A high-throughput ab initio review of platinum-group alloy systems [PDF]

, 2014
We report a comprehensive study of the binary systems of the platinum group metals with the transition metals, using high-throughput first-principles calculations.
Curtarolo, Stefano, Hart, Gus L. W., Levy, Ohad, Massalski, Thaddeus B.   +3 more
core   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Mechanisms of High Temperature Degradation of Thermal Barrier Coatings. [PDF]

, 2009
Thermal barrier coatings (TBCs) are crucial for increasing the turbine inlet temperature (and hence efficiency) of gas turbine engines. The thesis describes PhD research aimed at improving understanding of the thermal cycling failure mechanisms of ...
Wu, Rudder T.C., Wu, Rudder T.C.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Micromagnetic survey experience in the mapping of the South Sopcha platinum-bearing intrusion, Monchegorsk ore district

Vestnik MGTU
The norite-pyroxenite zone hosting platinum group element (PGE) mineralization is located at the base of the South Sopcha intrusion being a part of the Monchegorsk layered complex.
Groshev N. Yu., Sushchenko A. M., Raevsky A. B., Ivanov A. N., Chernyavsky A. V.   +4 more
doaj   +1 more source