Results 51 to 60 of about 5,331,821 (317)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Doświadczenia i korzyści płynące z wdrażania programu „Original Play”™ wśród dzieci i młodzieży w Polsce

Podstawy Edukacji, 2008
Brak
Jolanta Graczykowska
doaj  

Prevalence and correlates of probable post-traumatic stress disorder and common mental disorders in a population with a high prevalence of HIV in Zimbabwe

European Journal of Psychotraumatology, 2018
Background: We investigated the prevalence of and factors associated with post-traumatic stress disorder (PTSD) and common mental disorders (CMDs), which include depression and anxiety disorders, in a setting with a prevalence of high human ...
R. Verhey, L. Gibson, J. Brakarsh, D. Chibanda, S. Seedat   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Qualitative approaches to developmental psychology: negotiating power, ethics, and geographies when researching in South African schools for autistic children

Methods in Psychology
Despite the growing call for inclusivity in developmental psychology, there remains a scarcity of methodological guidance. We address this gap through a reflexive case study based on our qualitative research in South African autism schools.
Stephanie Katharina Nowack, Nidhi Singal, Jenny Louise Gibson, John-Joe Dawson-Squibb   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The effectiveness of non-directive play therapy [PDF]

, 2003
Plan BA variety of therapeutic interventions appear to be effective when used with children who are struggling with issues such as abuse, neglect, divorce, family violence, grief, and severe trauma.
Lesniak, Jennifer L.
core  

Cultural Variations in Parental Support of Children\u27s Play

, 2002
The purpose of this reading is to highlight the importance of play for children\u27s development and to examine the role of parents in supporting children\u27s play in various cultures.
Maureen Vandermaas-Peeler, Vandermaas-Peeler, Maureen   +1 more
core   +1 more source

Modelo Relacional Integral para la Gobernanza: Gaztedi 2030

GIGAPP Estudios Working Papers, 2019
El Modelo Relacional GAZTEDI de la Diputación Foral de Bizkaia persigue modernizar la Administración Pública según los nuevos y exigentes criterios de eficiencia y coherencia en la gestión pública, transparencia, rendición de cuentas y participación ...
Estibaliz Biguri, Danel Alberdi
doaj  

Validation of the posttraumatic stress disorder checklist – 5 (PCL-5) in a primary care population with high HIV prevalence in Zimbabwe

BMC Psychiatry, 2018
Background There is a dearth of validated tools measuring posttraumatic stress disorder (PTSD) in low and middle-income countries in sub-Saharan Africa.
Ruth Verhey, Dixon Chibanda, Lorna Gibson, Jonathan Brakarsh, Soraya Seedat   +4 more
doaj   +1 more source