Results 71 to 80 of about 6,185,542 (297)
, 2023 The right rest and leisure, to engage in play is usually missing from any discussions of children's rights. It is all too easy to fall into the trap of thinking only of those rights which are about protections; from poverty, from war and from abuse of ...
Shier, Harry, Hart, Roger, PLAY-TRAIN
core
Creativity and the Simon Task Performance
Psychological Topics, 2023 The aim of this study was to examine performance in the Simon task regarding individual differences in creative behavior measured by The Inventory of Creative Activities and Achievements (ICAA; Diedrich et al., 2018). The study included 105 students and
Maša Milas Patrk, Ana Šimunić
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A scoping review of methods and measures used to capture children's play during school breaktimes [PDF]
Play is linked to healthy child development and is recognised in the UN Convention on the Rights of the Child. School breaktimes provide regular opportunities for children to play, and as such, they have been the context of a large and interdisciplinary ...
Oliver, Brooke +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Tackling reflexivity in human-centred design research to benefit user needs and sensitivities
BaseLongevity research highlights complexities of assessing the elderly’s future needs and impact of design solutions. Especially, the potential for (self-) transformation within human relations or interactions through design work (e.g., through technology ...
Antonia Clasina Södergren
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2023 This paper embarks on an exploration into the vibrant world of do-it-yourself (DIY) play practices within the urban milieu of Tāmaki Makaurau previously known as Auckland, Aotearoa New Zealand.
Zhang, Linda +5 more
core
Cricklewood Irish Community Play constitution [PDF]
Typewritten constitution of the Cricklewood Community Play Association, including aims and objectives and equal opportunities policy.
Cricklewood Community Play Association, CCPA +1 more
core +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source