Results 81 to 90 of about 8,044,780 (313)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Doubly Real: Game Studies and Literary Anthropology; or, Why We Play Games

open access: yesEludamos, 2009
Few game studies scholars will regret that the infelicitous ludology vs. narratology debate has been left behind. However, one misconception concerning the nature of literary theory continues to haunt game studies.
Philipp Schweighauser
doaj   +1 more source

Dietary factors and Type 2 diabetes in the Middle East : what is the evidence for an association? - A systematic review. [PDF]

open access: yes, 2013
This review aims to search and summarise the available evidence on the association between dietary factors and type 2 diabetes mellitus (T2DM) in Middle Eastern populations, where diabetes prevalence is among the highest in the world.
AI-Othaimeen   +27 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Celebrity and Disconnection in Joan Didion’s Hollywood Writings

open access: yesIperstoria
In her 1979 non-fiction essay “The White Album,” Californian writer Joan Didion (1934-2021) describes her living on Franklin Avenue and the peculiar atmosphere in Beverly Hills during the summer of 1969. The infamous murders on Cielo Drive put an abrupt
Adélaïde Malval
doaj   +1 more source

20 years of Scandinavian studies at Vilnius University − feast, play and puzzles

open access: yesTaikomoji kalbotyra, 2014
The present review article has been re-published in this electronic journal with kind permission of the author of the article and the editors of the following book: Sausverde, Ērika and Ieva Steponavičiūtė (eds) 2014.
Ērika Sausverde
doaj   +1 more source

Lost in the chaos : flawed literature should not generate new disorders [PDF]

open access: yes, 2017
Kuss and colleagues’ paper ‘Chaos and confusion in DSM-5 diagnosis of Internet Gaming Disorder’ sets out to examine issues relating to the concept. We agree that there are serious issues and extend their arguments by suggesting that the field lacks basic
Kardefelt-Winther, Daniel   +1 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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