Results 71 to 80 of about 8,044,780 (313)
On-line role-play as a teaching method in engineering studies
Journal of Technology and Science Education, 2011 We propose to adapt the role-play teaching methodology to engineering studies, trying to overcome obstacles like its exclusive association with fantasy games or its demand of social skills.
Adolfo Cobo +4 more
doaj +1 more source
Case studies: understanding players and the contexts in which they play. Workshop on Crossing Domains: Diverse Perspectives on Players [PDF]
, 2015 Over recent years, the study of games and players has become an established domain with HCI research. However, while a range of methods has been employed within this area, questions remain as to how to develop in-depth understandings of players and the ...
Cox, Anna, Iacovides, Ioanna
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
In or Out? Experiential Learning and Three Consequences of Communicating Group Identity [PDF]
, 2012 Group identity is intimately tied with self identity. Yet, people often understand their identity as individual without appreciation for the role others play in their identity.
Coghill, Kelli +3 more
core +1 more source
Sex differences in the structure and stability of children’s playground social networks and their overlap with friendship relations [PDF]
, 2008 Gender segregated peer networks during middle childhood have been highlighted as important for explaining later sex differences in behaviour, yet few studies have examined the structural composition of these networks and their implications.
Baines, Ed, Blatchford, Peter
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes [PDF]
, 1986 Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles.
Blatt, Cila +13 more
core
Subjective Causality and Counterfactuals in the Social Sciences [PDF]
, 2018 The article explores the role that subjective evidence of causality and associated counterfactuals and counterpotentials might play in the social sciences where comparative cases are scarce.
Abell, Peter, Engel, Ofer
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source