Results 11 to 20 of about 210,488 (345)

Early risk assessment for COVID-19 patients from emergency department data using machine learning

Scientific Reports, 2021
Since its emergence in late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic with more than 55 million reported cases and 1.3 million estimated deaths worldwide.
Frank S. Heldt, Marcela P. Vizcaychipi, Sophie Peacock, Mattia Cinelli, Lachlan McLachlan, Fernando Andreotti, Stojan Jovanović, Robert Dürichen, Nadezda Lipunova, Robert A. Fletcher, Anne Hancock, Alex McCarthy, Richard A. Pointon, Alexander Brown, James Eaton, Roberto Liddi, Lucy Mackillop, Lionel Tarassenko, Rabia T. Khan   +18 more
doaj   +1 more source

Defining the therapeutic reference range for cariprazine

European Psychiatry, 2023
Introduction According to the Consensus Guideline, the “therapeutic reference range” (TRR) defines ranges of drug blood concentrations that specify a lower limit below which a drug-induced therapeutic response is unlikely to occur and an upper limit ...
M. Kapás, A. Horváth, D. Djuric, R. Csehi, Á. Barabássy   +4 more
doaj   +1 more source

PLC

, 2021
What do PLCs do?
openaire   +2 more sources

Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

Cancer Research, 2006
Angiogenesis and signaling through the RAF/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK cascade have been reported to play important roles in the development of hepatocellular carcinomas (HCC).
Li Liu, Yichen Cao, Charles Chen, Xiaomei Zhang, Angela Mcnabola, D. Wilkie, S. Wilhelm, M. Lynch, Christopher A. Carter   +8 more
semanticscholar   +1 more source

A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study

Arthritis Research & Therapy, 2022
Background Publications suggest immunomodulation co-therapy improves responder rates in uncontrolled/refractory gout patients undergoing pegloticase treatment.
John K. Botson, John R. P. Tesser, Ralph Bennett, Howard M. Kenney, Paul M. Peloso, Katie Obermeyer, Yang Song, Brian LaMoreaux, Lin Zhao, Yan Xin, Jason Chamberlain, Srini Ramanathan, Michael E. Weinblatt, Jeff Peterson   +13 more
doaj   +1 more source

Similarity-based prediction of ejection fraction in heart failure patients

Informatics in Medicine Unlocked, 2022
Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments.
Jamie Wallis, Andres Azqueta-Gavaldon, Thanusha Ananthakumar, Robert Dürichen, Luca Albergante   +4 more
doaj   +1 more source

Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis

Respiratory Research, 2020
Background Patients with chronic obstructive pulmonary disease (COPD) are at risk of exacerbations and pneumonia; how the risk factors interact is unclear.
Benjamin F. Hartley, Neil C. Barnes, Sally Lettis, Chris H. Compton, Alberto Papi, Paul Jones   +5 more
doaj   +1 more source

CLIK on PLCs! Attacking Control Logic with Decompilation and Virtual PLC

Proceedings 2019 Workshop on Binary Analysis Research, 2019
—This paper presents CLIK , a new remote attack on the control logic of a programmable logic controller (PLC) in industrial control systems. The control logic defines how a PLC controls a physical process such as a nuclear plant.
Sushma Kalle, Nehal Ameen, Hyunguk Yoo, Irfan Ahmed   +3 more
semanticscholar   +1 more source

The PLC as a Smart Service in Industry 4.0 Production Systems

Applied Sciences, 2019
Industrial controls, and in particular, Programmable Logic controllers (PLC) currently form an important technological basis for the automation of industrial processes. Even in the age of industry 4.0 and industrial internet, it can be assumed that these
Reinhard Langmann, Michael Stiller
semanticscholar   +1 more source

Towards Automated Safety Vetting of PLC Code in Real-World Plants

IEEE Symposium on Security and Privacy, 2019
Safety violations in programmable logic controllers (PLCs), caused either by faults or attacks, have recently garnered significant attention. However, prior efforts at PLC code vetting suffer from many drawbacks.
Mu Zhang, Chien-Ying Chen, Bin-Chou Kao, Yassine Qamsane, Yuru Shao, Yikai Lin, E. Shi, Sibin Mohan, K. Barton, J. Moyne, Z. Morley Mao   +10 more
semanticscholar   +1 more source