Results 251 to 260 of about 65,328 (279)

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Nature Genetics, 2018
Marie Verbanck, Chia-Yen Chen, Benjamin M Neale   +2 more
exaly  

Pleiotropy

2001
openaire   +1 more source

Seven types of pleiotropy.

The International journal of developmental biology, 1998
Pleiotropy, a situation in which a single gene influences multiple phenotypic traits, can arise in a variety of ways. This paper discusses possible underlying mechanisms and proposes a classification of the various phenomena involved.
openaire   +1 more source

Pleiotropy in complex traits: challenges and strategies

Nature Reviews Genetics, 2013
Nadia Solovieff, Chris Cotsapas, Phil H Lee   +2 more
exaly  

Pleiotropy

2012
openaire   +1 more source

Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling

Cell, 2017
Aaron M Ring, Akanksha Chhabra, Philipp Starkl   +2 more
exaly  

Pathways and Pleiotropy

2021
openaire   +1 more source

Assessing pleiotropy and its evolutionary consequences: pleiotropy is not necessarily limited, nor need it hinder the evolution of complexity

Nature Reviews Genetics, 2012
Xu-sheng Zhang
exaly  

Pleiotropy

2011
openaire   +1 more source

Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines

Immunity, 2019
Masaaki Murakami, Daisuke Kamimura, Toshio Hirano   +2 more
exaly