Results 231 to 240 of about 50,540 (257)

Bayesian Bidirectional Mendelian Randomization Under Correlated and Uncorrelated Pleiotropy Using GWAS Summary Statistics. [PDF]

Stat Med
Chen S.
europepmc   +1 more source

Shared Genetic Basis of Autoimmune Diseases and Follicular Lymphoma by Mendelian Randomization and Multi-Omics. [PDF]

Genes (Basel)
Jiang C, Sun Z, Gao Z, Wang J, Liang J, Feng Y.   +5 more
europepmc   +1 more source

Genetic evidence for the association between per- and polyfluoroalkyl substances exposure and rheumatoid arthritis risk: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Xu H, Liu J, Qiu X, He J, Sun W.
europepmc   +1 more source

Limited evidence for causal effects of circulating inflammatory cytokines on the risk of selected hematologic malignancies: a two-sample Mendelian randomization study. [PDF]

Blood Res
Zhang H, Zhang L, Zhao D, Ma B, Wang J, Liu X, Yin W, Shen Y, Yang L, Dong W, Wang C.   +10 more
europepmc   +1 more source

A novel framework leveraging non-causal associations reveals shared pathways linking inflammation and cancer risk

Yarmolinsky J, Cavallo FR, Koskeridis F, Yu X, Bouras E, Richenberg G, Costantini I, Ray D, Woolf B, Karhunen V, Ellis L, Haycock PC, Hemani G, Davey Smith G, Tsilidis KK, Zuber V, McKay JD, Dehghan A, Tzoulaki I.   +18 more
europepmc   +1 more source

Pleiotropy robust methods for multivariable Mendelian randomization [PDF]

Statistics in Medicine, 2021
Mendelian randomization is a powerful tool for inferring the presence, or otherwise, of causal effects from observational data. However, the nature of genetic variants is such that pleiotropy remains a barrier to valid causal effect estimation. There are
Stephen Burgess, Andrew J Grant
exaly   +6 more sources

Mendelian randomization incorporating uncertainty about pleiotropy [PDF]

Statistics in Medicine, 2017
Mendelian randomization (MR) requires strong assumptions about the genetic instruments, of which the most difficult to justify relate to pleiotropy.
Dipender Gill, Nuala A. Sheehan, Cosetta Minelli   +2 more
exaly   +6 more sources

Some of the next articles are maybe not open access.

Related searches:

Conserved pleiotropy of an ancient plant homeobox gene uncovered by cis-regulatory dissection

Cell, 2021
Zachary Lippman, Yuval Eshed, Idan Efroni   +2 more
exaly