Results 51 to 60 of about 10,594 (224)

Accurate discrimination of the wake-sleep states of mice using non-invasive whole-body plethysmography [PDF]

open access: yes, 2017
A major limitation in the study of sleep breathing disorders in mouse models of pathology is the need to combine whole-body plethysmography (WBP) to measure respiration with electroencephalography/electromyography (EEG/EMG) to discriminate wake-sleep ...
Swoap, Steven J   +17 more
core   +1 more source

Assessing Static Lung Hyperinflation by Whole-Body Plethysmography, Helium Dilution, and Impulse Oscillometry System (IOS) in Patients with COPD

open access: yesInternational Journal of COPD, 2020
Michela D’Ascanio,1 Fausta Viccaro,1 Noemi Calabrò,1 Giulio Guerrieri,1 Claudia Salvucci,1 Dario Pizzirusso,1 Rita Mancini,1 Claudia De Vitis,1 Aldo Pezzuto,2 Alberto Ricci1 1Department of Clinical and Molecular Medicine, Sant’Andrea ...
D'Ascanio M   +9 more
doaj  

Normative reference equations of airway dynamics assessed by whole‐body plethysmography during spontaneous breathing evaluated in infants, children, and adults

open access: yesPhysiological Reports, 2021
Effective specific airway resistance (sReff), its reciprocal the effective specific airway conductance (sGeff) are computed as ratios between the integral of the resistive aerodynamic work of breathing (sWOB) and the integral of the tidal flow/volume ...
Richard Kraemer   +2 more
doaj   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang   +6 more
wiley   +1 more source

Modification and Application of a Commercial Whole-body Plethysmograph to Monitor Respiratory Abnormalities in Neonatal Mice

open access: yesBio-Protocol, 2017
Proper breathing is essential for mammals to acquire oxygen after birth and requires coordinated actions among several tissues, including diaphragm, intercostal muscles, trachea, bronchi, lung and respiration-regulating neurons located in the medulla ...
Yen-Ting Lai, Yi-Shuian Huang
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

open access: yesEpilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire   +7 more
wiley   +1 more source

Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy

open access: yesFrontiers in Immunology, 2023
IntroductionProphylactic strategies to prevent the development of allergies by establishing tolerance remain an unmet medical need. We previously reported that the transfer of autologous hematopoietic stem cells (HSC) expressing the major timothy grass ...
Lisa Prickler   +19 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist‐Based Agents and Body Composition: Filling More Gaps

open access: yesObesity, EarlyView.
ABSTRACT The last 2 decades have seen historic advances in the treatment of obesity. We are entering an era of defining obesity not by weight‐based outcomes but by changes in body composition. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are forming the platform for obesity treatments based on their high level of efficacy. Body composition can
Robert L. Dubin   +4 more
wiley   +1 more source

Comparison between total lung capacity calculated bysingle-breath methane dilutionand by whole-body plethysmography [PDF]

open access: yes, 2017
Total lungkapacitet (TLC) är den totala volymen gas i lungorna efter en maximal inspiration. Den kan beräknas med kroppspletysmograf utifrån tryckförändringar och Boyles lag respektive utifrån gasspädning med metan alternativt helium som spädningsgas ...
Källmyr, Nicole, Jansson, Therése
core  

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