Results 81 to 90 of about 23,583 (245)

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats

Experimental Physiology
Obstructive sleep apnoea (OSA) is a prevalent cardiorespiratory disorder associated with significant neurocognitive consequences. Despite the higher prevalence of OSA in men, there is a strong association between OSA and Alzheimer's disease (AD), which ...
Emily C. Cheung, Joan B. Escobar, Bridget R. Alber, Caitlin Ribeiro, Ishan Abdullah, Grant Kowalik, Jeannette Rodriguez, Grey Harral, Makeda Melkie, Aman Gill, John T. Ketzenberger, John Bethea, Vsevolod Y Polotsky, Vivek Jain, Kathryn Schunke, Matthew W. Kay, David Mendelowitz   +16 more
doaj   +1 more source

Nocturnal Sleep Breathing Patterns in Healthy Adolescents Residing at Very High Altitudes in Bolivia

Journal of Sleep Research, EarlyView.
ABSTRACT Data on sleep and respiratory patterns among adolescents residing at very high altitude (> 3500 m) remain scarce, and altitude‐related physiological differences may influence these parameters. Studying adolescents at different very high altitudes is crucial, as subtle environmental variations could affect sleep‐related oxygenation and ...
Keaton Patterson, Santiago Ucrós Rodríguez, E. Nicolás Arancibia‐Levit, Fernanda Aliaga Raduan, José Antonio Viruez Soto, Max Gassmann, Silvia Ulrich, Michael Furian, Edith M. Schneider Gasser   +8 more
wiley   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up

Experimental Physiology, EarlyView.
Abstract In patients previously hospitalised for COVID‐19, a 12‐week high‐intensity interval training (HIIT) intervention has previously been shown to increase left ventricular mass (LVM) immediately after the intervention. In the present study, we examined the effects of the same HIIT scheme on LVM, pulmonary diffusing capacity, symptom severity and ...
Iben Elmerdahl Rasmussen, Mathilde Løk, Cody Garett Durrer, Anna Agnes Lytzen, Frederik Foged, Vera Graungaard Schelde, Josephine Bjørn Budde, Rasmus Syberg Rasmussen, Emma Fredskild Høvighoff, Villads Rasmussen, Mark Lyngbæk, Simon Jønck, Rikke Krogh‐Madsen, Birgitte Lindegaard, Peter Godsk Jørgensen, Lars Køber, Niels Vejlstrup, Bente Klarlund Pedersen, Mathias Ried‐Larsen, Morten Asp Vonsild Lund, Ronan M. G. Berg, Regitse Højgaard Christensen   +21 more
wiley   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

The therapeutic role of exercise training during menopause for reducing vascular disease

Experimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing, Bert Bond, Kerrie L. Moreau, Jeff S. Coombes, Jenna L. Taylor   +4 more
wiley   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

Experimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley, Tomoki Watada, Go Ito, Ai Shimada, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Tadayoshi Miyamoto   +7 more
wiley   +1 more source

Plethysmographic and Spirometric Reference Equations for Healthy Algerian Adults Using Lambda-Mu-Sigma (Generalized Additive Models for Location, Scale, and Shape): Comparison with Global Lung Initiative 2012 and Global Lung Initiative 2021 Standards

Journal of Advanced Lung Health
Introduction: Spirometric reference values are essential for diagnosing and managing respiratory diseases. However, existing equations, such as those from the Global Lung Initiative (GLI), may not fully represent North African populations.
Abdelbassat Ketfi, Sabrina Benzamouche, Siham Bey   +2 more
doaj   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source