Results 121 to 130 of about 104,742 (284)

Clinical management of CMML—State of the art

British Journal of Haematology, EarlyView.
Patients with chronic myelomonocytic leukaemia (CMML) typically present with clinical feature including splenomegaly, constitutional symptoms and autoimmune phenomena, as well as with pathological blood counts and biological features in the marrow. These characteristics may influence the assignment to prognostic categories such as the CPSSmol and also ...
K. Nachtkamp, F. Schulz, N. Gattermann, U. Germing   +3 more
wiley   +1 more source

Value of Cell Block in the Diagnosis of Malignant Pleural Effusion

Chinese Journal of Lung Cancer, 2015
Malignant pleural effusion (MPE ) is due tumor which arises from the mesothelium or metastases from tumor origniating other sites. In large, for undiagnosed unilateral pleural effusions, the most frequent and important diagnosis to be established or ...
Fangyuan CHENG, Qian WANG, Diansheng ZHONG   +2 more
doaj   +1 more source

Recent advances in multimodality imaging‐guided therapy in pericarditis

European Journal of Clinical Investigation, EarlyView.
Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi, Aldo L. Schenone, Paul Cremer, Tom Kai Ming Wang, Allan Klein   +4 more
wiley   +1 more source

A Rare Tumor in a Septuagenarian Female 16 Years After Radical Mastectomy for Breast Carcinoma. [PDF]

Clin Case Rep
ABSTRACT Pleuropulmonary spindle cell carcinoma (SpCC) is a very rare tumor that belongs to a subgroup of sarcomatoid carcinomas of non‐small cell carcinomas of the lung. Breast carcinoma is one of the most common malignancies associated with metachronous second primary cancers.
Rahimirad M, Daneshvar S, Rahimirad S, Halimi M, Sharifi A.   +4 more
europepmc   +2 more sources

Treatment‐Free Remission in Chronic Myeloid Leukemia: Revisiting the “W” Questions

European Journal of Haematology, EarlyView.
ABSTRACT Chronic myeloid leukemia (CML) has undergone a transformation from a fatal disease to a chronic, manageable condition with the advent of tyrosine kinase inhibitors (TKIs), particularly imatinib. This shift has significantly improved survival rates, and for some patients, achieving deep molecular response (DMR) has made treatment‐free remission
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Nicola Amodio, Caterina Labanca, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Fortunato Morabito, Massimo Gentile   +9 more
wiley   +1 more source

Loss of MTAP expression is not an accurate surrogate for CDKN2A homozygous deletions in peritoneal mesothelioma

Histopathology, EarlyView.
MTAP immunohistochemistry (IHC) was evaluated as a diagnostic tool for peritoneal mesothelioma by comparing it with CDKN2A homozygous deletion (HD) detected by FISH. Results showed low concordance between MTAP IHC and CDKN2A HD, suggesting MTAP IHC is not reliable for predicting CDKN2A HD in peritoneal mesothelioma. Further studies are needed.
Andrea Quaranta, Andrea Marzullo, Francesco Fortarezza, Sonia Maniglio, Concetta Caporusso, Floriana Pentimone, Federica Pezzuto, Domenica Cavone, Teresa Lettini, Mario Magistro, Cecilia Salzillo, Luigi Vimercati, Paolo Graziano, Gabriella Serio, Antonio d'Amati   +14 more
wiley   +1 more source

Metastatic Squamous Cell Carcinoma Treated With Pembrolizumab in a Patient With Xeroderma Pigmentosum

Pediatric Dermatology, Volume 42, Issue 4, Page 831-834, July/August 2025.
ABSTRACT A 5‐year‐old male with xeroderma pigmentosum from Honduras presented with a rapidly growing mass on the left post‐auricular neck, associated with left‐sided hearing loss. MRI revealed a large mass with invasion of the external auditory canal, temporal bone, and metastasis to lymph nodes. Biopsy confirmed moderately differentiated squamous cell
Ngan Do, Robert J. Smith, Sara Choi, Maria Queenan, Mary Larijani   +4 more
wiley   +1 more source

Contemporary Concise Review 2024: New Techniques in Interventional Pulmonology

Respirology, EarlyView.
SUMMARY OF KEY POINTS Navigational bronchoscopy and cone beam computed tomography (CBCT) guided bronchoscopy show comparable yields to percutaneous transthoracic needle biopsy of lung nodules. Robotic assisted bronchoscopy (RAB) with advanced imaging (CBCT or digital tomosynthesis) improves diagnostic yield further.
Phan Nguyen, Pallav L. Shah
wiley   +1 more source

Retrospective Study Evaluating Outcomes Following Palliative Radiotherapy With or Without Chemotherapy for Dogs With Presumed Cardiac Hemangiosarcoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine cardiac hemangiosarcoma (cHSA) represents a complex clinical challenge in that those afflicted have an acute risk of death due to cardiac tamponade and high morbidity and mortality given the frequency of metastasis. Previous studies show that radiation therapy (RT) can decrease the risk of tamponade; however, an optimal approach has yet
Cory N. Wakamatsu, Brianna M. Potter, Del Leary, Mary‐Keara Boss, Tiffany W. Martin   +4 more
wiley   +1 more source

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with this disease.
Pawel Kordowitzki, Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner, Ioana Elena Braicu, Jalid Sehouli   +6 more
wiley   +1 more source