Results 121 to 130 of about 45,501 (263)

May Biochemical Variables and Pleural Fluid Cell Count Be Used in the Benign- Malign Differentiation of Pleural Effusions Associated with Lung Cancer?

open access: yesBezmiâlem Science, 2019
Objective:Pleural effusion is frequently encountered in patients with lung cancer. Malignant-benign differentiation of the fluid is very important for treatment decision because malignant fluid is considered as the inoperability criterion.
Sami DENİZ   +5 more
doaj   +1 more source

Swirling pattern in patients with exudative pleural effusion

open access: yesThe Egyptian Journal of Bronchology, 2017
Objective Thoracic ultrasound is the gold-standard method for studying pleural effusions. It is more sensitive than chest radiography or computed tomography. Aim The aim of the paper was to determine whether the echogenic swirling pattern identifiable on
Khaled Kamel   +3 more
doaj   +1 more source

Cardiac Angiosarcoma: A Diagnostic and Therapeutic Challenge

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Kang Ying Tan, Yi‐Chang Liu
wiley   +1 more source

Multiple Kinase Small Molecule Inhibitor Tinengotinib (TT‐00420) Alone or With Chemotherapy Inhibit the Growth of SCLC

open access: yesCancer Science, Volume 116, Issue 4, Page 951-965, April 2025.
Tinengotinib, a multi‐targeted kinase inhibitor, demonstrates significant efficacy in inhibiting small cell lung cancer (SCLC) cell proliferation, particularly in the SCLC‐N subtype with high NEUROD1 expression. When combined with etoposide/cisplatin, it synergistically suppresses SCLC growth.
Hui Li   +13 more
wiley   +1 more source

AXL‐Mediated Drug Resistance in ALK‐Rearranged NSCLC Enhanced by GAS6 From Macrophages and MMP11 Positive Fibroblasts

open access: yesCancer Science, Volume 116, Issue 4, Page 1034-1047, April 2025.
Activation of the GAS6/AXL signaling pathway promotes resistance to ALK‐TKIs both in vitro and in vivo. Single‐cell RNA sequencing revealed that specific cancer‐associated fibroblasts (CAFs) and a subset of macrophages are the primary sources of Gas6 in the tumor microenvironment (TME).
Takahiro Utsumi   +6 more
wiley   +1 more source

Diagnostic Value of Sialic Acid in Pleural Effusion

open access: yesChinese Journal of Lung Cancer, 2010
The present study was conducted in 30 patients of malignant pleural effusion and 30 patients of non malignant pleural effusion. Pleural fluid and blood samples were taken at the time of admission, before starting any treatment.
S KHARB, S TANDON, A BANSAL
doaj  

Novel TEAD1 Inhibitor VT103 Enhances Dabrafenib Efficacy in BRAF V600E Mutated Lung Adenocarcinoma via Survivin Downregulation

open access: yesCancer Science, EarlyView.
We established a novel patient‐derived BRAF V600E‐mutated lung adenocarcinoma cell line and demonstrated that combining a novel TEAD1 inhibitor (VT103) with dabrafenib enhances therapeutic efficacy through survivin downregulation. Our tissue microarray analysis revealed a strong correlation between YAP1, TEAD1, and survivin expression in lung ...
Kazutaka Hosoya   +19 more
wiley   +1 more source

Value of Cell Block in the Diagnosis of Malignant Pleural Effusion

open access: yesChinese Journal of Lung Cancer, 2015
Malignant pleural effusion (MPE ) is due tumor which arises from the mesothelium or metastases from tumor origniating other sites. In large, for undiagnosed unilateral pleural effusions, the most frequent and important diagnosis to be established or ...
Fangyuan CHENG   +2 more
doaj   +1 more source

Recent advances in multimodality imaging‐guided therapy in pericarditis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi   +4 more
wiley   +1 more source

Tensioning diaphragmoplasty for treating bilateral phrenic nerve paralysis in a dog

open access: yesJournal of Small Animal Practice, EarlyView.
A spayed female Miniature dachshund presented with a large mediastinal mass. During thymectomy, the left phrenic nerve, which was encircled by the neoplastic tissue, was resected en bloc with the tumour and the right phrenic nerve was damaged by thermal coagulation from electrosurgery. Postoperatively, the dog exhibited significant respiratory distress
S. Matsumoto   +3 more
wiley   +1 more source

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