Results 121 to 130 of about 2,262,450 (373)

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source

Revisiting tuberculous pleurisy: pleural fluid characteristics and diagnostic yield of mycobacterial culture in an endemic area

Thorax, 2012
Background Tuberculous pleurisy is traditionally indicated by extreme lymphocytosis in pleural fluid and low yield of effusion culture. However, there is considerable inconsistency among previous study results.
S. Ruan, Y. Chuang, Jann-Yuan Wang, Jou-Wei Lin, J. Chien, Chun-Ta Huang, Y. Kuo, Li‐Na Lee, Chong-Jen Yu   +8 more
semanticscholar   +1 more source

Mass cytometric detection of homologous recombination proficiency in circulating tumor cells to predict chemoresistance of metastatic breast cancer patients

International Journal of Cancer, EarlyView.
What's New? Circulating tumor cells can offer insights into treatment responses and metastatic recurrence, but current analysis methods are limited. Here, the authors tested a newly developed mass cytometry panel comprising biomarkers such as γH2AX and RAD51 in longitudinally monitored metastatic breast cancer patients.
Kathrin Niedermayer, Henning Schäffler, Georgios Vlachos, Sara Greco, Kerstin Pfister, Barbara Volz, Leonie Ott, Hans Neubauer, Bernhard Polzer, André Koch, Sabine Riethdorf, Tanja Fehm, Wolfgang Janni, Thomas W. P. Friedl, Brigitte Rack, Ellen Heitzer, Fabienne Schochter, Lisa Wiesmüller   +17 more
wiley   +1 more source

A massive hemorrhagic pleural effusion does not exclude the diagnosis of tuberculosis: a case report [PDF]

, 2009
We report a case of an immunocompetent 18-year-old man with a massive hemorrhagic, exudative, lymphocytic pleural effusion. Blind transthoracic pleural biopsy showed granuloma formation, while the pleural fluid culture was positive for Mycobacterium ...
Anastasia Amfilochiou, Antony Kopanakis, Charalampos Mermigkis, Georgios Patentalakis, Kostas Psathakis, Manolis Kastanakis, Michael Patentalakis, Napoleon Karagiannidis, Vlassis Polychronopoulos   +8 more
core   +2 more sources

Psammoma Bodies in Pleural Fluid Associated with a Mesothelioma: Case Report [PDF]

, 1979
John C. Donaldson, David Kaminsky, Robert C. Elliott, Thomas Walsh, John G. Newby   +4 more
openalex   +2 more sources

Evaluation of different laboratory methods for rapid diagnosis of tuberculous pleurisy*

International Journal of Mycobacteriology, 2016
Background/Objective: Tuberculous pleurisy is a diagnostic challenge due to its nonspecific clinical presentation, paucibacillary nature of the effusion together with the inefficiency of conventional laboratory methods motivating the evaluation of ...
Safaa Amer, Azza El Hefnawy, Nashwa Abdel Wahab, Hadir Okasha, Amira Baz   +4 more
doaj   +1 more source

Diagnostic utility of the cell block method versus the conventional smear study in pleural fluid cytology

Journal of Cytology, 2012
Background: The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis.
Udasimath Shivakumarswamy, S. Arakeri, Mahesh H Karigowdar, B. Yelikar   +3 more
semanticscholar   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

A mass that has no (EBUS) echo. [PDF]

, 2018
We report findings for a patient that underwent endobronchial ultrasound (EBUS) guided transbronchial needle aspiration (TBNA) for diagnostic purposes after an abnormal chest CT. The patient initially presented with cough and shortness of breath.
Rosenblum, Matthew K, Seeley, Eric J, Wang, Sue X   +2 more
core   +2 more sources

Diagnostic Accuracy of Adenosine Deaminase and Lymphocyte Proportion in Pleural Fluid for Tuberculous Pleurisy in Different Prevalence Scenarios

PLoS ONE, 2012
Background Tuberculous pleural effusion (TPE) is a paucibacillary manifestation of tuberculosis, so isolation of Mycobacterium tuberculosis is difficult, biomarkers being an alternative for diagnosis.
A. Garcia-Zamalloa, J. Taboada-Gómez
semanticscholar   +1 more source