Results 121 to 130 of about 42,358 (170)

Platelet Compatibility of PLGA, Chitosan and PLGA–Chitosan Nanoparticles

Nanomedicine, 2009
The increasing interest in biodegradable nanoparticles containing biomaterials such as poly(D,L-lactide-co-glycolide) (PLGA) and chitosan for drug delivery raises issues regarding the blood compatibility of these nanoparticles, since some nanoparticles, including carbon nanoparticles, can affect human platelet aggregation and cause vascular thrombosis.
Xue, Li, Anna, Radomski, Owen I, Corrigan, Lidia, Tajber, Fabio, De Sousa Menezes, Sibylle, Endter, Carlos, Medina, Marek W, Radomski   +7 more
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Adhesion of PLGA or Eudragit®/PLGA nanoparticles to Staphylococcus and Pseudomonas

International Journal of Pharmaceutics, 2008
The aim of present study was to examine whether cationic Eudragit containing poly(lactide-co-glycolide) (PLGA) nanoparticles can adhere to Pseudomonas aeruginosa and Staphylococcus aureus. In order to prepare fluorescent nanoparticles, fluorescein was covalently coupled to PLGA.
Dillen, Kathleen, Bridts, Chris, van der Veken, Pieter, Cos, Paul, Vandervoort, Jo, Augustyns, Koen, Stevens, Wim, Ludwig, Annick   +7 more
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Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA–mPEG nanoparticles

International Journal of Pharmaceutics, 2001
The effect of nanoparticle dose on the biodistribution and pharmacokinetics of conventional PLGA and stealth poly(Lactide-co-glycolide)-monomethoxypoly(ethyleneglycol) (PLGA-mPEG) nanoparticles was investigated. The precipitation-solvent diffusion method was used to prepare PLGA and PLGA-mPEG nanoparticles labeled with 125I-cholesterylaniline.
Z, Panagi, A, Beletsi, G, Evangelatos, E, Livaniou, D S, Ithakissios, K, Avgoustakis   +5 more
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Influence of LA and GA Sequence in the PLGA Block on the Properties of Thermogelling PLGA-PEG-PLGA Block Copolymers

Biomacromolecules, 2011
This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths but different sequences of D,L ...
Lin, Yu, Zheng, Zhang, Jiandong, Ding
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Effect of PLGA block molecular weight on gelling temperature of PLGA‐PEG‐PLGA thermoresponsive copolymers

Journal of Polymer Science Part A: Polymer Chemistry, 2018
ABSTRACTThermoresponsive, biodegradable polymeric hydrogel networks are used widely in medicinal applications. Poly(d,l‐lactic acid‐co‐glycolic acid)‐b‐poly(ethylene glycol)‐b‐poly(d,l‐lactic acid‐co‐glycolic acid) (PLGA‐PEG‐PLGA) triblock copolymers exhibit a sol–gel transition upon heating.
Noam Y. Steinman, Moran Haim‐Zada, Isaac A. Goldstein, Ayelet H. Goldberg, Tom Haber, Jacob M. Berlin, Abraham J. Domb   +6 more
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PLGA–PEG–PLGA hydrogel for ocular drug delivery of dexamethasone acetate

Drug Development and Industrial Pharmacy, 2010
This study aims to investigate the suitability of thermosensitive triblock polymer poly-(DL-lactic acid-co-glycolic acid) (PLGA)-polyethylene glycol (PEG)-PLGA as a matrix material for ocular delivery of dexamethasone acetate (DXA).The copolymer was synthesized and evaluated for its thermosensitive and gelation properties.
Yuan, Gao, Yan, Sun, Fuzheng, Ren, Shen, Gao   +3 more
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Release of rifampicin from chitosan, PLGA and chitosan-coated PLGA microparticles

Colloids and Surfaces B: Biointerfaces, 2008
Recently three groups of rifampicin (RIF)-loaded microparticles (MPs), consisting of chitosan (CHT), PLGA and PLGA/CHT mixtures, were assessed in terms of RIF-loading and retention during nebulisation. The CHT-coated PLGA MPs were found to exhibit high RIF-loading ability together with nebulisation ability, stability, and mucoadhesive properties.
MANCA, MARIA LETIZIA, Loy G, Zaru M, FADDA, ANNA MARIA, Antimisiaris SG   +4 more
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PLGA-Mikropartikel

2022
Diese Arbeit handelt von der Charakterisierung der Größe sowie Größenverteilung und freisetzungsspezifischer Eigenschaften von Testosteronbeladenen Mikropartikeln, welche mit PLGA unterschiedlicher Molekulargewichte mittels Solvent Evaporation Methode hergestellt wurden. Weiters wurde die Möglichkeit einer Oberflächenoptimierung von PLGA-Mikropartikel,
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Synthesis and characterization of elastic PLGA/PCL/PLGA tri-block copolymers

Journal of Biomaterials Science, Polymer Edition, 2002
Various ABA-type tri-block copolymers composed of poly(L-lactide) (PLA) or poly (lactide-co-glycolide) (PLGA) as the side A block and poly(epsilon-caprolactone) (PCL) as the middle B block were synthesized to produce rapidly degrading elastic matrices useful for tissue engineering scaffolds.
Choi, SH, Park, TG
openaire   +3 more sources

Modulating the Thermoresponsive Characteristics of PLGA–PEG-PLGA Hydrogels via Manipulation of PLGA Monomer Sequences

Biomacromolecules
Hydrogels are promising materials for biomedical applications, particularly in drug delivery and tissue engineering. This study highlights thermoresponsive hydrogels, specifically poly(lactic-co-glycolic acid) (PLGA)-poly(ethylene glycol) (PEG)-PLGA triblock copolymers, and introduces a feed rate-controlled polymerization (FRCP) method. By utilizing an
SeongHoon Jo, Soonjong Roh, Jaemin Shim, Ji Woong Yu, Youngmee Jung, Woo Young Jang, Bumjoon Seo, You-Yeon Won, Jin Yoo   +8 more
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