Results 141 to 150 of about 42,358 (170)
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Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA–PEG diblock copolymers

International Journal of Pharmaceutics, 2005
The basic characteristics and the biodistribution properties of nanoparticles prepared from mixtures of poly(lactide-co-glycolide) (PLGA) with poly(lactide-co-glycolide)-poly(ethylene glycol) (PLGA-PEG) copolymers were investigated. A PLGA(45)-PEG(5) copolymer of relatively low PEG content and a PLGA(5)-PEG(5) copolymer of relatively high PEG content ...
A, Beletsi, Z, Panagi, K, Avgoustakis
openaire   +2 more sources

Biodegradable Triblock Copolymer of PLGA-PEG-PLGA Enhances Gene Transfection Efficiency

Pharmaceutical Research, 2004
A tri-block copolymer of PLGA-PEG-PLGA was used as an excipient to enhance the gene transfection efficiency of various cationic polymeric carriers.Luciferase plasmid DNA was complexed with polyethylenimine for gene transfection. Various concentrations of PLGA-PEG-PLGA copolymer up to 0.5% were added in the transfection medium to explore whether the ...
Jeong, JH, Kim, SW, Park, TG
openaire   +3 more sources

Characterisation, cytotoxicity and apoptosis studies of methotrexate-loaded PLGA and PLGA-PEG nanoparticles

Journal of Microencapsulation, 2013
Methotrexate (MTX) widely used in the treatments of various types of malignancies, but high toxicity and short plasma half-life have limited its use. This study was aimed at developing a polymeric drug delivery system for improving the therapeutic index of this potent drug. To achieve these goals, PLGA and PLGA-PEG nanoparticles were prepared using the
Majid, Afshari   +2 more
openaire   +2 more sources

PKPD of PLGA-PEG-PLGA Copolymeric Micelles

2022
Shirleen Miriam Marques, Lalit Kumar
openaire   +1 more source

PLGA-Gentamicin and PLGA-Hydroxyapatite-Gentamicin Microspheres for Medical Applications

Pharmaceutical Chemistry Journal, 2022
A. Turcu-Ştiolică   +9 more
openaire   +1 more source

Thermosensitive vancomycin@PLGA-PEG-PLGA/HA hydrogel as an all-in-one treatment for osteomyelitis

International Journal of Pharmaceutics, 2022
Qingyu Wang   +2 more
exaly  

PLGA-Based Composites for Various Biomedical Applications

International Journal of Molecular Sciences, 2022
Milène Costa da Silva   +2 more
exaly  

Phenomenology of the Initial Burst Release of Drugs from PLGA Microparticles

ACS Biomaterials Science and Engineering, 2020
Jin Yoo, You-Yeon Won
exaly  

PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery?

Colloids and Surfaces B: Biointerfaces, 2008
Maria-Letizia Manca   +4 more
openaire   +1 more source

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