Results 171 to 180 of about 179,155 (337)

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, Volume 13, Issue 7, 3 February 2026.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar, Sepideh Ahmadi, Nikzad Abbariki, Navid Rabiee, Sidi A. Bencherif   +4 more
wiley   +1 more source

Design and Tuning of a Modified Power-Based PLL for Single-Phase Grid-Connected Power Conditioning Systems [PDF]

, 2012
Saeed Golestan, Mohammad Monfared, Francisco D. Freijedo, Josep M. Guerrero   +3 more
openalex   +1 more source

Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC

Glia, Volume 74, Issue 2, February 2026.
Mechanical properties of Mlc1‐null astrocytes are altered. Cytoskeleton‐related pathways are dysregulated in Mlc1‐null astrocytes. Mlc1‐null astrocytes show alterations in focal adhesions, which link the cytoskeleton to the extracellular matrix. ABSTRACT Loss of function of the astrocyte protein MLC1 causes Megalencephalic Leukoencephalopathy with ...
Quinty Bisseling, Emma M. J. Passchier, Freya M. Kirwan, Nelda Antonovaite, Serena Camerini, Maria S. Brignone, Amélie Freal, Huibert D. Mansvelder, Elena Ambrosini, Marjo S. van der Knaap, Rogier Min   +10 more
wiley   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Comparative Performance Evaluation of Orthogonal-Signal-Generators-Based Single-Phase PLL Algorithms—A Survey

, 2015
Yang Han, Mingyu Luo, Xin Zhao, Josep M. Guerrero, Lin Xu   +4 more
openalex   +2 more sources

Bilayer Fiber‐Reinforced Composite‐Hydrogel Scaffolds With Bioactive Glass for Bone Tissue Regeneration

Journal of Biomedical Materials Research Part A, Volume 114, Issue 2, February 2026.
ABSTRACT Bone tissue regeneration for large defects presents a significant challenge, demanding scaffolds that combine robust mechanical support alongside a bioactive environment. Hydrogels represent a promising solution for bone regeneration due to their biocompatibility, tunable properties, and crosslinked three‐dimensional (3D) networks mimicking ...
Mona Gibreel, Roope Ohlsbom, Leila Perea‐Lowery, Lippo Lassila, Paula Puistola, Karoliina Hopia, Susanna Miettinen, Anni Mörö, Pekka K. Vallittu   +8 more
wiley   +1 more source

Paclitaxel-Loaded Polyelectrolyte Nanocarriers: Uptake Mechanisms, Cytotoxicity, and Genotoxicity in Human Endothelial and Breast Cancer Cells. [PDF]

Nanotechnol Sci Appl
Szwed M, Poczta-Krawczyk A, Kania KD, Bukowski K, Bednarska-Szczepaniak K, Marczak A, Szczepanowicz K.   +6 more
europepmc   +1 more source

Gold Nanoparticles Grafted with PLL-b-PNIPAM: Interplay on Thermal/pH Dual-Response and Optical Properties [PDF]

, 2018
Huijuan Li, Pengyun Li, Liying Li, Abdul Haleem, Wei‐Dong He   +4 more
openalex   +1 more source

Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

Small, Volume 22, Issue 9, 12 February 2026.
This study introduces multifunctional, bioactive factor‐loaded porous microshuttles fabricated via a one‐step emulsification and chemical etching method. The poly(lactic‐co‐glycolic acid) microshuttles, featuring tunable pore sizes, enable loading and release of bioactive factors, and thereby enhance osteogenic marker expression and promote endothelial
Ke Song, Francesca Giacomini, Esra Güben Kaçmaz, Pamela Habibović, Roman Truckenmüller, Zeinab Niloofar Tahmasebi Birgani   +5 more
wiley   +1 more source