Abnormal Action Potentials Associated with the Shaker Complex Locus of Drosophila [PDF]
Intracellular recordings of action potentials were made from the cervical giant axon in Shaker (Sh) mutants and normal Drosophila. The mutants showed abnormally long delays in repolarization.
Ferrus, Alberto+2 more
core +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
PLOIDY AND GENE EXPRESSION IN CLEMENTINE
Polyploidy has long been recognized as an important force in the evolution of flowering plants and often results in novel phenotypes having advantages in adaptation and major interest for agriculture. Many crops, including citrus, are bred to a higher level of ploidy in search of desirable traits.
Niñoles Rodenes, Regina+4 more
openaire +3 more sources
Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen+11 more
wiley +1 more source
Paspalum notatum Flügge is a grass species organized as an agamic complex. The objective of the current research was to survey the frequencies and variation of cytosine methylation at CCGG sequences in diploid and tetraploid genotypes, and to determine ...
M. P. Rodriguez+3 more
doaj +1 more source
Identification of Paternal Uniparental Disomy on Chromosome 22 and a De-novo Deletion on Chromosome 18 in Individuals with Orofacial Clefts [PDF]
Background: Orofacial clefts are the most common malformations of the head and neck region. Genetic and environmental factors have been implicated in the etiology of these traits.Methods: We recently conducted genotyping of individuals from the African ...
Abate, Firke+28 more
core +2 more sources
Drought is a major cause of crop losses across agricultural regions. Rhizosheath formation enhances plant resistance to drought. Polyploids may tolerate stress more effectively through increased interactions with bacteria. However, the contributions of tetraploid rice associated microbiota to rhizosheath formation under soil drying remain unclear ...
Feiyun Xu+23 more
wiley +1 more source
A comparison of methods for determining ploidy in white sturgeon (Acipenser transmontanus) [PDF]
Release of sturgeon with abnormal ploidy into the wild may result in reduced fitness due to lowered fertility in the F2 and subsequent generations. Further, there is evidence that ploidy affects reproductive development and caviar yield.
Fiske, JA+6 more
core
Comparison of two high-throughput semiconductor chip sequencing platforms in noninvasive prenatal testing for Down syndrome in early pregnancy [PDF]
Background: Noninvasive prenatal testing (NIPT) to detect fetal aneuploidy using next-generation sequencing on ion semiconductor platforms has become common. There are several sequencers that can generate sufficient DNA reads for NIPT.
A Fortuny+48 more
core +1 more source
Ploidy determination of Canadida albicans [PDF]
The dimorphic yeast Candida albicans, as a member of the fungi imperfecti, has been assumed to be in the haploid, or imperfect, state. The deoxyribonucleic acid content of this species has been measured by flow microfluorometry, a technique capable of analyzing single cells.
A F Olaiya, S J Sogin
openaire +3 more sources