Results 151 to 160 of about 90,784 (353)

Evaluation of Transgenerational Gene Editing Efficiency and Inheritance of Edits Using a Split Cas9/gRNA Crossing System in Zea mays

open access: yes
Plant Biotechnology Journal, EarlyView.
Christian Damian Lorenzo   +9 more
wiley   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman   +15 more
wiley   +1 more source

Ploidy of Seeds from Odd-polyploid American Elm [PDF]

open access: gold, 2020
Alan T. Whittemore, Zheng-Lian Xia
openalex   +1 more source

A high‐recovery, high‐density targeted genotyping platform for cranberry

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract The American cranberry (Vaccinium macrocarpon) is a commercially important berry species native to North America. Cranberry is a popular fruit crop with many known health benefits. Thus far, genotyping‐by‐sequencing (GBS) was the only high‐throughput genotyping technique available in cranberry.
Shaun J. Clare   +15 more
wiley   +1 more source

Potato dihaploids uncover diverse alleles to facilitate diploid potato breeding

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Commercial potato (Solanum tuberosum) in North America is a clonal autotetraploid crop, which complicates breeding. Efforts are underway to convert potato to a diploid inbred‐hybrid crop, allowing breeders to more quickly meet market and environmental demands.
Sapphire Coronejo   +27 more
wiley   +1 more source

First whole genome sequence of a diploid crop wild relative of the Andean tuber “oca”: Annotation and comparative genomic analysis of Oxalis oulophora

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Oxalis oulophora, a diploid species closely related to the octoploid Andean tuber crop oca (Oxalis tuberosa), was selected for whole‐genome sequencing to aid in understanding the origins of polyploidy and domestication in oca and its relatives (crop wild relatives).
Dilrini Vanrooyen, Eve Emshwiller
wiley   +1 more source

High‐throughput single‐cell DNA methylation and chromatin accessibility co‐profiling with SpliCOOL‐seq

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen   +6 more
wiley   +1 more source

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