Results 151 to 160 of about 90,784 (353)
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman +15 more
wiley +1 more source
Ploidy of Seeds from Odd-polyploid American Elm [PDF]
Alan T. Whittemore, Zheng-Lian Xia
openalex +1 more source
A high‐recovery, high‐density targeted genotyping platform for cranberry
Abstract The American cranberry (Vaccinium macrocarpon) is a commercially important berry species native to North America. Cranberry is a popular fruit crop with many known health benefits. Thus far, genotyping‐by‐sequencing (GBS) was the only high‐throughput genotyping technique available in cranberry.
Shaun J. Clare +15 more
wiley +1 more source
Ploidy and proliferation in human bladder tumors as measured by flow-cytofluorometric DNA-analysis and its relations to histopathology and cytology [PDF]
B. Tribukait +2 more
openalex +1 more source
Potato dihaploids uncover diverse alleles to facilitate diploid potato breeding
Abstract Commercial potato (Solanum tuberosum) in North America is a clonal autotetraploid crop, which complicates breeding. Efforts are underway to convert potato to a diploid inbred‐hybrid crop, allowing breeders to more quickly meet market and environmental demands.
Sapphire Coronejo +27 more
wiley +1 more source
Abstract Oxalis oulophora, a diploid species closely related to the octoploid Andean tuber crop oca (Oxalis tuberosa), was selected for whole‐genome sequencing to aid in understanding the origins of polyploidy and domestication in oca and its relatives (crop wild relatives).
Dilrini Vanrooyen, Eve Emshwiller
wiley +1 more source
Clinical Significance of DNA Ploidy in Epithelial Ovarian Malignancy [PDF]
Byung Young Lee, Hyun Chan Kim
openalex +1 more source
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen +6 more
wiley +1 more source

