Results 131 to 140 of about 36,442 (241)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Comprehensive analyses of different putative ploidy levels in organelle genomes of an important medicinal plant Polygonatum kingianum Collett & Hemsl. [PDF]

BMC Plant Biol
Zhao J, Chen ZH, Zhang MX, Wang LH, Yang XY, Wang JG, Zhu YY, Li XY, Zhao Y.   +8 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, Volume 20, Issue 8, Page 2023-2039, August 2026.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Ecological opportunity and the onset of polyploid niche expansion waves. [PDF]

Proc Natl Acad Sci U S A
Kauai F, Van de Peer Y, Bonte D.
europepmc   +1 more source

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Application of non-invasive preimplantation genetic screening for aneuploidy through spent embryo culture media analysis at 48 and 54 hours after embryo cleavage. [PDF]

Br J Biomed Sci
Satirapod C, Niransuk P, Tantanavipas S, Sensorn I, Chantratita W, Trachoo O.   +5 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Corrigendum: LocoGSE, a sequence-based genome size estimator for plants

Frontiers in Plant Science
Pierre Guenzi-Tiberi, Benjamin Istace, Inger Greve Alsos, The PhyloNorway Consortium, Eric Coissac, Sébastien Lavergne, The PhyloAlps Consortium, Jean-Marc Aury, France Denoeud   +8 more
doaj   +1 more source

Genome Sequence Data Reveal Complex and Variable Ploidy in the Amoebozoan Acanthamoeba castellanii. [PDF]

Genome Biol Evol
Colp MJ, Archibald JM.
europepmc   +1 more source

Haemophilia A in a Female German Shepherd With Homozygosity for the FVIII p.C567Y Variant in Exon 11 of the F8 Gene

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Haemophilia A is an extremely rare disorder in females, as the causative F8 gene is located on the X chromosome. Female carriers, also known as ‘conductors,’ are typically heterozygous and therefore do not show clinical signs of the disease. However, in mild forms of haemophilia A, affected males may survive and mate.
Bertram Brenig, Sabrina Pach
wiley   +1 more source