Genome-wide association mapping and targeted loss of function studies identify <i>Shroom3</i> as a driver of hyperpolyploidy and ventricular dilation. [PDF]
Purdy AL +18 more
europepmc +1 more source
Tests for Categorical Data Beyond Pearson: A Distance Covariance and Energy Distance Approach
ABSTRACT Categorical variables are of uttermost importance in biomedical research. When two of them are considered, it is often the case that one wants to test whether or not they are statistically dependent. We show weaknesses of classical methods—such as Pearson's and the G$G$‐test—and we propose testing strategies based on distances that lack those ...
Fernando Castro‐Prado +4 more
wiley +1 more source
Multi-omics profiling reveals an auxin-salicylic acid signaling hub driving flavonoid depletion and accelerated vigor loss in tetraploid Chinese cabbage seeds. [PDF]
Meng C +6 more
europepmc +1 more source
ABSTRACT Introduction Systemic cervical cancer management continues to be challenging. Numerous chemotherapies have been approved, but predicting response is difficult due to the lack of biomarkers. Here, we analyze the genetic and protein profiles of 20 cervical cancer cell lines (CCCLs) and explore their correlation with drug response patterns to ...
Suzy Scholl +10 more
wiley +1 more source
Decoding hepatocyte ploidy [PDF]
openaire +2 more sources
Polyploidisation of Lobelia speciosa and introgression in Lobelia erinus hybrids
K. Olbricht +3 more
doaj +1 more source
Comparative Diagnostic Performance of DNA Ploidy Analysis and p16/Ki67 Dual-Staining with Cytology in hrHPV-Defined Subgroups: A Single-Center Evaluation. [PDF]
Wang Y, Qi C.
europepmc +1 more source
Linking genome size variation to phenotypic selection on target traits
Abstract Genome size (GS) is known to be highly variable among angiosperm species. However, this variation can also occur within species. Both interspecific and intraspecific variations in GS have been often found to be linked to phenotypic traits. Therefore, selective pressures acting on these target traits may indirectly shape GS evolution within and
Lucrezia Laccetti +5 more
wiley +1 more source
Meiosis-specific genes play roles in ploidy reduction in <i>Cryptococcus neoformans</i> titan cells. [PDF]
Bian Z +7 more
europepmc +1 more source

