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Ploidy and the Causes of Genomic Evolution [PDF]

open access: yesJournal of Heredity, 2009
Genomes vary dramatically in size and in content. This variation is driven in part by numerous polyploidization events that have happened over the course of eukaryotic evolution. Experimental evolution studies, primarily using the yeast Saccharomyces cerevisiae, provide insights into the immediate fitness effects of ploidy mutations, the ability of ...
Aleeza Gerstein   +2 more
exaly   +3 more sources
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Cytology, Ploidy and Ploidy Manipulation

2016
The genus Actinidia is remarkable for the variation in ploidy both within and between taxa. There is a structured reticulate pattern of diploids, tetraploids, hexaploids, octoploids and decaploids in diminishing frequency within the genus. The basic chromosome number x = 29 suggests that diploids of Actinidia are in fact palaeopolyploids.
Allan Ross Ferguson, Hongwen Huang
openaire   +1 more source

The determination of megakaryocyte ploidy

The International Journal of Cell Cloning, 1990
Methods which have been used to determine megakaryocyte ploidy in animals and humans are reviewed. Although the number of megakaryocyte nuclear units counted in bone marrow squashes is roughly proportional to ploidy, accurate determinations of DNA content require the use of microphotometry or flow cytometry.
J M, Paulus   +2 more
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Cytokinesis, ploidy and aneuploidy

The Journal of Pathology, 2011
AbstractCytokinesis is the last step of cell division that physically separates the daughter cells. As such, it ensures the proper inheritance of both nuclear and cytoplasmic contents. Accomplishment of cytokinesis in eukaryotes is dictated by several key events: establishment of the division plane, furrow ingression through contraction of an ...
Benjamin, Lacroix, Amy Shaub, Maddox
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Monkeying around with ploidy

Molecular Ecology, 2012
Inferences of whole genome duplication (WGD) events accompany the annotation of every newly sequenced plant genome, but much remains unknown about the evolutionary processes and pathways relating to WGD (Soltis et al. 2010). What ecological, biogeographical and genetic factors cause WGD to occur in nature? How does WGD affect gene expression?
openaire   +2 more sources

Ploidy Regulation of Gene Expression

Science, 1999
Microarray-based gene expression analysis identified genes showing ploidy-dependent expression in isogenic Saccharomyces cerevisiae strains that varied in ploidy from haploid to tetraploid. These genes were induced or repressed in proportion to the number of chromosome sets, regardless of the mating type.
T, Galitski   +4 more
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The effect of cytokines on the ploidy of megakaryocytes

The International Journal of Cell Cloning, 1990
The effects of recombinant cytokines on the ploidy of human megakaryocytes derived from megakaryocyte progenitors were studied using serum-free agar cultures. Nonadherent and T cell-depleted marrow cells were cultured for 14 days. Megakaryocyte colonies were identified in situ by the alkaline phosphatase anti-alkaline phosphatase technique, using ...
M, Teramura, H, Mizoguchi
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Ploidy in the hearts of elderly patients

Virchows Archiv B Cell Pathology Including Molecular Pathology, 1982
The DNA-ploidy of the left and right ventricular wall in 48 patients aged 80-98 years was investigated by scanning cytophotometry. The great variation in nuclear ploidy previously described in the heart muscle was shown to persist during the ninth decade.
B, Rosenberg, P, Pfitzer
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Megakaryocytic Ploidy in Myelodysplastic Syndromes

Leukemia & Lymphoma, 1993
The megakaryocytic ploidy was microfluorometrically measured in 12 normal controls and 15 myelodysplastic syndrome (MDS) patients using DAPI (4',6-diamidino-2-phenylindole) staining after destaining of the Wright-Giemsa (WG) stain. MDS patients had slightly more immature megakaryocytes when compared with normal controls.
Y, Kobayashi   +3 more
openaire   +2 more sources

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