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DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy [PDF]
, 2014 Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN).
Abdel-Rahman +44 more
core +2 more sources
Ploidy dynamics and evolvability in fungi [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2016 Rapid responses to acute stresses are essential for stress survival and are critical to the ability of fungal pathogens to adapt to new environments or hosts. The rapid emergence of drug resistance is used as a model for how fungi adapt and survive stress conditions that inhibit the growth of progenitor cells. Aneuploidy and loss of heterozygosity (LOH)
Noa Blutraich Wertheimer +2 more
openaire +3 more sources
A Target Capture-Based Method to Estimate Ploidy From Herbarium Specimens
Frontiers in Plant Science, 2019 Whole genome duplication (WGD) events are common in many plant lineages, but the ploidy status and possible occurrence of intraspecific ploidy variation are unknown for most species.
Juan Viruel +16 more
doaj +1 more source
Differential Requirement for the Cell Wall Integrity Sensor Wsc1p in Diploids Versus Haploids
Journal of Fungi, 2021 The primary role of the Cell Wall Integrity Pathway (CWI) in Saccharomyces cerevisiae is monitoring the state of the cell wall in response to general life cycle stresses (growth and mating) and imposed stresses (temperature changes and chemicals). Of the
Allison E. Hall +2 more
doaj +1 more source
Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus [PDF]
, 2020 Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation.
Booker, William +11 more
core +4 more sources
Molecular Oncology, 2011 AbstractAneuploidy, often preceded by tetraploidy, is one of the hallmarks of solid tumors. Indeed, both aneuploidy and tetraploidy are oncogenic occurrences that are sufficient to drive neoplastic transformation and cancer progression. True to form, the tumor suppressor p53 obstructs propagation of these dangerous chromosomal events by either ...
Yael Aylon, Moshe Oren
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Gender and ploidy in cancer survival [PDF]
Cellular Oncology, 2011 Females carry a better prognosis than men for many cancer types. We hypothesized that chromosomal changes, in particular numerical alterations of the sex chromosomes or the presence of near-triploidy may contribute to these gender differences.To characterize the influence of gender a literature search was performed for survival data of 27 tumor types ...
Susanne Schulze, Iver Petersen
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Frontiers in Microbiology, 2022 The biotechnologically important and naturally transformable cyanobacterium, Synechococcus elongatus PCC 7942, possesses multiple genome copies irrespective of its growth rate or condition.
Sadaf Riaz +7 more
doaj +1 more source
Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). [PDF]
, 2017 BackgroundAcipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of ...
Amemiya, Chris T +7 more
core +4 more sources
Histology and histopathology, 1999 We reviewed the literature concerning the history of determination of the ploidy of human megakaryocytes and its relationship with diseases. The ploidy of rabbit megakaryocytes was analyzed by microspectrophotometry in 1964, and the analysis of the ploidy in human megakaryocytes was first performed in 1968. Presently, microphotometry and flow cytometry
Kobayashi, Y., Kondo, M.
openaire +3 more sources