Results 341 to 350 of about 115,209 (391)
Proliferative polyploid cells give rise to tumors via ploidy reduction
Nature Communications, 2021 Polyploidy is a hallmark of cancer, and closely related to chromosomal instability involved in cancer progression. Importantly, polyploid cells also exist in some normal tissues.
Tomonori Matsumoto +2 more
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Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy
Nature Communications, 2021 Single-cell RNA-seq reveals the role of pathogenic cell populations in development and progression of chronic diseases. In order to expand our knowledge on cellular heterogeneity, we have developed a single-nucleus RNA-seq2 method tailored for the ...
Maria L Richter +2 more
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Sublinear scaling of the cellular proteome with ploidy
Nature Communications, 2022 Ploidy changes are frequent in nature and contribute to evolution, functional specialization and tumorigenesis. Analysis of model organisms of different ploidies revealed that increased ploidy leads to an increase in cell and nuclear volume, reduced ...
Prince Saforo Amponsah, , Matthias Mann
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In vitro Ploidy Manipulation for Crop Improvement
Frontiers in Plant Science, 2020 In vitro regeneration systems provide a powerful tool for manipulating ploidy to facilitate breeding and development of new crops. Polyploid induction can expand breeding opportunities, assist with the development of seedless triploid cultivars, enhance ...
Darren Touchell, Thomas G Ranney
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The population genetics of ploidy change in unicellular fungi.
FEMS Microbiology Reviews, 2021Changes in ploidy are a significant type of genetic variation, describing the number of chromosome sets per cell. Ploidy evolves in natural populations, clinical populations, and lab experiments, particularly in fungi.
A. Gerstein, Nathaniel P. Sharp
semanticscholar +1 more source
New Phytologist, 2016 Summary Angiosperm genome sizes (GS) range c. 2400‐fold, and as nucleic acids are amongst the most phosphorus‐ (P) and nitrogen (N)‐demanding cellular biomolecules, we test the hypothesis that a key influence on plant biomass and species composition is ...
Mark Trimmer +2 more
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Cytology, Ploidy and Ploidy Manipulation
2016The genus Actinidia is remarkable for the variation in ploidy both within and between taxa. There is a structured reticulate pattern of diploids, tetraploids, hexaploids, octoploids and decaploids in diminishing frequency within the genus. The basic chromosome number x = 29 suggests that diploids of Actinidia are in fact palaeopolyploids.
Allan Ross Ferguson, Hongwen Huang
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The determination of megakaryocyte ploidy
The International Journal of Cell Cloning, 1990Methods which have been used to determine megakaryocyte ploidy in animals and humans are reviewed. Although the number of megakaryocyte nuclear units counted in bone marrow squashes is roughly proportional to ploidy, accurate determinations of DNA content require the use of microphotometry or flow cytometry.
J M, Paulus +2 more
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Cytokinesis, ploidy and aneuploidy
The Journal of Pathology, 2011AbstractCytokinesis is the last step of cell division that physically separates the daughter cells. As such, it ensures the proper inheritance of both nuclear and cytoplasmic contents. Accomplishment of cytokinesis in eukaryotes is dictated by several key events: establishment of the division plane, furrow ingression through contraction of an ...
Benjamin, Lacroix, Amy Shaub, Maddox
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Molecular Ecology, 2012
Inferences of whole genome duplication (WGD) events accompany the annotation of every newly sequenced plant genome, but much remains unknown about the evolutionary processes and pathways relating to WGD (Soltis et al. 2010). What ecological, biogeographical and genetic factors cause WGD to occur in nature? How does WGD affect gene expression?
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Inferences of whole genome duplication (WGD) events accompany the annotation of every newly sequenced plant genome, but much remains unknown about the evolutionary processes and pathways relating to WGD (Soltis et al. 2010). What ecological, biogeographical and genetic factors cause WGD to occur in nature? How does WGD affect gene expression?
openaire +2 more sources