Results 71 to 80 of about 87,114 (318)

A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans. [PDF]

, 2019
Eukaryotes have evolved elaborate mechanisms to ensure that chromosomes segregate with high fidelity during mitosis and meiosis, and yet specific aneuploidies can be adaptive during environmental stress.
Brimacombe, Cedric A, Burke, Jordan E, Burrack, Laura S, Catania, Sandra, Madhani, Hiten D, Noble, Suzanne M, O'Meara, Teresa R, Parsa, Jahan-Yar, Witchley, Jessica N   +8 more
core   +3 more sources

Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes)

Advanced Science, EarlyView.
This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv, Jia Li, Yanping Li, Yu Huang, Qiang Lai, Zhengyong Wen, Jun Wang, Yang He, Jinrong Shi, Zejin Huang, Ying Jiang, Yves Van de Peer, Qiong Shi, Biwen Xie, Yongming Wang   +14 more
wiley   +1 more source

Outstanding intraindividual genetic diversity in fissiparous planarians (Dugesia, Platyhelminthes) with facultative sex.

, 2019
Predicted genetic consequences of asexuality include high intraindividual genetic diversity (i.e., the Meselson effect) and accumulation of deleterious mutations (i.e., Muller’s Ratchet), among others.
Leria, L., Riutort, M., Solà, E., Vila Farre, M.   +3 more
core   +1 more source

Phylogenetic relationships in Betula (Betulaceae) based on AFLP markers [PDF]

, 2008
The genus Betula comprises various species in boreal and temperate climate zones of the Northern Hemisphere. The taxonomy of Betula is controversial and complicated by parallel evolution of morphological traits, polyploidization events, and extensive ...
Gilissen, L.J.W.J., Koopman, W.J.M., Schenk, M.F., Smulders, M.J.M., Thienpont, C.N.   +4 more
core   +2 more sources

CATECHOLAMINE SECRETION AND PLOIDY IN PHAEOCHROMOCYTOMA

International Journal of Clinical Practice, 2000
SUMMARYThe aim was to evaluate 24 hr urine catecholamine, HMMA and HVA excretion in relation to ploidy in phaeochromocytoma. Data from five diploid and nine tetraploid tumours showed a significant reduction in urine noradrenaline (p=0.02) and HMMA (p=0.03) in diploid tumours but no difference in adrenaline, dopamine and HVA excretion using the Mann ...
W P, Tormey, R J, Fitzgerald, G, Thomas, E W, Kay, M B, Leader   +4 more
openaire   +2 more sources

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

Advanced Science, EarlyView.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu, Qin‐Can Zhang, Zi‐Yu Zhu, Yang Wang, Zhong‐Wei Wang, Xi‐Yin Li, Zhi Li, Xiao‐Juan Zhang, Li Zhou, Jian‐Fang Gui   +9 more
wiley   +1 more source

Effect of Ploidy in Photoreactivation.

Experimental Biology and Medicine, 1952
SummaryThe survival fractions of diploid and haploid strains of S. cerevisiae after ultraviolet irradiation (2537 A.U.) have been obtained, compared, and modified by photoreactivation following the initial irradiation. The haploid survival follows a sigmoid curve and is smaller than the diploid at the same dose.
openaire   +3 more sources

A rewiring model of intratumoral interaction networks. [PDF]

, 2019
Intratumoral heterogeneity (ITH) has been regarded as a key cause of the failure and resistance of cancer therapy, but how it behaves and functions remains unclear.
Alizadeh, Badano, Bedard, Castro-Giner, Cleary, Couzin-Frankel, Easton, Enriquez-Navas, Fachal, Garcia-Closas, Gillies, Gosik, Greaves, Jørgensen, Kallioniemi, Komarova, Korolev, Lesseur, Li, Ling, McGranahan, Merlo, Nowak, Qazi, Saadatpour, Smith, Stadler, Tabassum, Vittecoq, Vogelstein, von Loga, von Neumann, Waclaw, Watson, Welch, Zhu   +35 more
core   +2 more sources

Patient With Prolidase Deficiency due to an Homozygous PEPD Variant, Induced by Paternal Uniparental Isodisomy of Chromosome 19

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive pathogenic variants in both alleles. Additionally, depending on the mechanisms by which UPD occurs, mosaic aneuploidies may
Marta Carreño‐Hidalgo, Raquel Muñoz‐Siles, Vanesa López‐González, Lidia Carreño‐Gago, Lluís Armengol Dulcet   +4 more
wiley   +1 more source

Identification of the relationship between Chinese Adiantum reniforme var. sinense and Canary Adiantum reniforme [PDF]

, 2015
© 2014 Wang et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
Chen, H-F, Liu, D-M, Schneider, Harald, Sun, Y, Wang, A-H, Wang, F-G, Xing, F-W, Zhai, J-W, Zhou, J-S   +8 more
core   +1 more source