Results 71 to 80 of about 115,209 (391)
, 2019 Predicted genetic consequences of asexuality include high intraindividual genetic diversity (i.e., the Meselson effect) and accumulation of deleterious mutations (i.e., Muller’s Ratchet), among others.
Leria, L. +3 more
core +1 more source
Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the anaphase-promoting complex/cyclosome [PDF]
, 2011 The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit ubiquitin ligase that regulates progression through the cell cycle by marking key cell division proteins for destruction.
Berckmans, Barbara +9 more
core +2 more sources
Advanced Science, EarlyView.Tumor‐informed circulating tumor DNA (ctDNA) analysis identifies patients with advanced non‐small cell lung cancer (NSCLC) who benefit from first‐line immunotherapy plus chemotherapy. Longitudinal ctDNA monitoring further reflects therapeutic response and predicts prognosis beyond imaging.
Kailun Fei +16 more
wiley +1 more source
Inferring Variation in Copy Number Using High Throughput Sequencing Data in R
Frontiers in Genetics, 2018 Inference of copy number variation presents a technical challenge because variant callers typically require the copy number of a genome or genomic region to be known a priori.
Brian J. Knaus, Niklaus J. Grünwald
doaj +1 more source
Global Diversification Rates of Ferns Across Spatial and Climatic Gradients
Advanced Science, EarlyView.Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley +1 more source
Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa
Advanced Science, EarlyView.This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong +17 more
wiley +1 more source
Journal of the American Society for Horticultural Science, 2023 There is demand for early-flowering cannabis (Cannabis sativa) cultivars to hasten harvest and avoid late-season detrimental weather conditions.
Lauren E. Kurtz +2 more
doaj +1 more source
A rewiring model of intratumoral interaction networks. [PDF]
, 2019 Intratumoral heterogeneity (ITH) has been regarded as a key cause of the failure and resistance of cancer therapy, but how it behaves and functions remains unclear.
Alizadeh +35 more
core +2 more sources
Advanced Science, EarlyView.Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Do plant ploidy and pollinator tongue length interact to cause low seed yield in red clover?
Ecosphere, 2021 The loss of long‐tongued pollinator species and dominance of a few short‐tongued generalist species, related to agricultural intensification in recent decades, may have consequences for the quality, quantity, and stability of yields in insect‐pollinated ...
Veronica Hederström +5 more
doaj +1 more source