Results 91 to 100 of about 37,977 (250)

Recent advances in the genomics of sugarcane (Saccharum)

Journal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang, Qin Zhang, Qiutao Xu, Han Zhao, Zhen Li, Jisen Zhang   +5 more
wiley   +1 more source

A robust biotechnology induces artificial genomic duplication via transient RNAi‐mediated suppression of OSD1 in rice

Journal of Integrative Plant Biology, EarlyView.
Plant Polyploidization via Gene Interference, a robust technology for inducing polyploidy in various rice accessions, uses transient RNAi‐mediated suppression of OSD1 to induce genomic duplication. Two strategies were used to directly induce fertile autotetraploid plants in the first generation, thereby substantially shortening the breeding cycle ...
Zijun Lu, Lianjun Zhu, Guobin Liang, Rou Chen, Yu Huang, Jia Yang, Liang Fu, Xiangxing Zhao, Runze Wu, Xiangdong Liu   +9 more
wiley   +1 more source

Exploring the intratumoral heterogeneity of DNA ploidy in prostate cancer

Cancer Reports
Background Prostate cancer is morphologically and molecularly heterogeneous. Genomic heterogeneity might be mirrored by variability in DNA ploidy. Aneuploidy is a hallmark of genomic instability and associated with tumor aggressiveness.
Tatjana Vlajnic, David C. Müller, Christian Ruiz, René Schönegg, Hans‐Helge Seifert, George N. Thalmann, Tobias Zellweger, Clémentine Le Magnen, Cyrill A. Rentsch, Lukas Bubendorf   +9 more
doaj   +1 more source

Genome‐scale insights into metabolic streamlining and photosynthetic energy balance in the extremophile green alga Picocystis salinarum (Picocystophyceae, Chlorophyta)

Journal of Phycology, EarlyView.
Abstract Picocystis salinarum is an early‐diverging chlorophyte and the sole described member of the Picocystophyceae, frequently dominating hypersaline and alkaline lakes despite extreme physicochemical constraints. To elucidate the genomic foundations of its ecological success, we generated a fully annotated, chromosome‐scale nuclear genome assembly ...
Claude Lemieux, Christian Otis, Monique Turmel   +2 more
wiley   +1 more source

Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA

Advanced Science
Most gene therapies exert their actions via manipulation of hepatocytes (parenchymal cells) and the reasons behind the suboptimal performance of synthetic mRNA in non‐parenchymal cells (NPC) such as Kupffer cells (KC), and liver macrophages, remain ...
Cheng Lin, Adrian Kuzmanović, Nan Wang, Liangliang Liao, Sabrina Ernst, Christian Penners, Alexander Jans, Thomas Hammoor, Petra Bumnuri Stach, Mona Peltzer, Ines Volkert, Elisabeth Zechendorf, Reham Hassan, Maiju Myllys, Christian Liedtke, Andreas Herrmann, Gurudas Chakraborty, Christian Trautwein, Jan Hengstler, Gerhard Müller‐Newen, Junqing Wang, Ahmed Ghallab, Matthias Bartneck   +22 more
doaj   +1 more source

Linking drought strategy to climate‐of‐origin in a widespread C4 grass: hydraulic traits, xylem anatomy and stomatal behaviour in Themeda triandra

New Phytologist, EarlyView.
Climate‐of‐origin of Themeda triandra populations used in this study. Summary Hydraulic, stomatal, and anatomical traits strongly influence plant performance under drought, but the extent to which these trait‐types are coordinated and relate to climate‐of‐origin remains vastly underexplored in herbaceous species relative to woody plants.
Vinod Jacob, Christopher J. Blackman, Brendan Choat, Brian J. Atwell, Eloise Foo, Alejandro Correa‐Lozano, Travis G. Britton, Emma E. Sumner, Ian J. Wright   +8 more
wiley   +1 more source

Excess endopolyploidy associated with cellular defects in neo‐autotetraploid Arabidopsis arenosa is in part corrected by a naturally evolved allele of CYCD3;2

New Phytologist, EarlyView.
Ploidy level distributions and endoreduplication profiles in diploid and tetraploid Arabidopsis arenosa. Summary Endopolyploidy (within‐organism polyploidy) is an often‐beneficial aspect of development. But polyploids, which have a higher baseline genome content, have been reported to have less endoreduplication than diploid relatives. Why has remained
Anis Meschichi, Marinela Dukić, Lars C. Schmid, Andreas L. Bachmann, Tadeas J. Priklopil, Hui San Tan, Kirsten Bomblies   +6 more
wiley   +1 more source

Biological Biomarkers in Proliferative Verrucous Leukoplakia: A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Objective To synthesise biological biomarker evidence in proliferative verrucous leukoplakia/proliferative leukoplakia and quantify malignant transformation using eligible longitudinal evidence. Methods Primary human biomarker studies and longitudinal studies reporting extractable malignant‐transformation events and denominators were ...
Madawi Faisal Alkeheli, Hisham I. Othman
wiley   +1 more source

High‐Contiguity Haplotype‐Resolved Genome Assembly of the Hexaploid Actinidia valvata Rootstock Sheds Light on Waterlogging Resistance Gene

Plant Biotechnology Journal, EarlyView.
ABSTRACT Polyploidisation, creating redundant or diverged copies of the genome, is a major driving force in plant evolution, diversification and environmental adaptation, including for the kiwifruit genus (Actinidia Lindl.). We present a high‐contiguity, haplotype‐resolved genome assembly of the hexaploid Actinidia valvata rootstock cultivar ...
Miaomiao Lin, Zhi Li, Cecilia H. Deng, Congcong Li, Zhengzhen Zhang, Yukuo Li, Qina Zhang, Peng Zhang, Leiming Sun, Mingyu Liu, Jinbao Fang, Xiujuan Qi   +11 more
wiley   +1 more source

Single‐Nucleus Transcriptome Analysis Provides New Insights Into B Chromosome Elimination in Sorghum

Plant Biotechnology Journal, EarlyView.
ABSTRACT B chromosomes are supernumerary entities found in many plant species, with some exhibiting tissue‐specific elimination. In Sorghum purpureosericeum, extensive B chromosome elimination occurs during embryogenesis affecting most of the embryonic organs, leaving the B chromosome maintained mainly in limited regions of meristems.
T. Bojdová, P. Abaffy, L. Valihrach, M. Karafiátová, J. Bartoš   +4 more
wiley   +1 more source