Results 51 to 60 of about 281 (94)

Mouse models for inherited monoamine neurotransmitter disorders

Journal of Inherited Metabolic Disease, Volume 47, Issue 3, Page 533-550, May 2024.
Abstract Several mouse models have been developed to study human defects of primary and secondary inherited monoamine neurotransmitter disorders (iMND). As the field continues to expand, current defects in corresponding mouse models include enzymes and a molecular co‐chaperone involved in monoamine synthesis and metabolism (PAH, TH, PITX3, AADC, DBH ...
Beat Thöny, Joanne Ng, Manju A. Kurian, Philippa Mills, Aurora Martinez   +4 more
wiley   +1 more source

Temperature‐smart plants: A new horizon with omics‐driven plant breeding

Physiologia Plantarum, Volume 176, Issue 1, January/February 2024.
Abstract The adverse effects of mounting environmental challenges, including extreme temperatures, threaten the global food supply due to their impact on plant growth and productivity. Temperature extremes disrupt plant genetics, leading to significant growth issues and eventually damaging phenotypes. Plants have developed complex signaling networks to
Ali Raza, Shanza Bashir, Tushar Khare, Benjamin Karikari, Rhys G. R. Copeland, Monica Jamla, Saghir Abbas, Sidra Charagh, Spurthi N. Nayak, Ivica Djalovic, Rosa M. Rivero, Kadambot H. M. Siddique, Rajeev K. Varshney   +12 more
wiley   +1 more source

Lumbar puncture seems to be safe and practical ın oldest-old patients: a protocol from a memory center

PurposePhysicians may hesitate to perform lumbar puncture (LP) with advancing age, particularly in daily practice in those aged 80 years or older. This study aimed to evaluate the characteristics and complications of LP in the oldest-old.MethodsThe ...
Ontan, Mehmet Selman, Yildirim, Acelya Gokdenız, Aydin, Ali Ekrem, Isik, Ahmet Turan, Ates Bulut, Esra, Dost, Fatma Sena, Kaya, Derya   +6 more
core   +1 more source

Disorders affecting vitamin B₆ metabolism [PDF]

, 2019
Vitamin B6 is present in our diet in many forms however only pyridoxal 5’‐phosphate (PLP) can function as a cofactor for enzymes. The intestine absorbs non‐phosphorylated B6 vitamers, which are converted by specific enzymes to the active PLP form.
Clayton, P, Mills, PB, Wilson, M, Plecko, B   +3 more
core   +1 more source

Synteny and genetic analysis as approaches to signal transduction in cyanobacteria [PDF]

Las cianobacterias, microorganismos que realizan la fotosíntesis oxigénica, tienen que adaptar su metabolismo a los distintos retos ambientales a los que se enfrentan, como la limitación de nutrientes o los ciclos de luz oscuridad.
Llop Estevez, Antonio
core   +1 more source

Maintenance of cellular vitamin B₆ levels and mitochondrial oxidative function depend on pyridoxal 5'-phosphate homeostasis protein. [PDF]

J Biol Chem, 2023
Ciapaite J, van Roermund CWT, Bosma M, Gerrits J, Houten SM, IJlst L, Waterham HR, van Karnebeek CDM, Wanders RJA, Zwartkruis FJT, Jans JJ, Verhoeven-Duif NM.   +11 more
europepmc   +1 more source

The causal effects of 2,821 protein level ratios on non-small cell lung cancer: a two-sample Mendelian randomization study. [PDF]

Transl Cancer Res
Zou X, Shen J, Li X, Diao Y, Zhang L.
europepmc   +1 more source

Precision diagnosis and treatment of vitamin metabolism-related epilepsy. [PDF]

Acta Epileptol
Gan Y, Li G, Wei Z, Feng Y, Shi Y, Deng Y.   +5 more
europepmc   +1 more source

A target prediction method to inhibit the replication process of SARS-CoV-2 via metabolic differential analysis

, 2023
Zheng H, Qi Y, Zhao Y.
europepmc   +1 more source

Protein-protein interfaces as druggable targets: A common motif of the pyridoxal-5’-phosphate-dependent enzymes to receive the coenzyme from its producers

, 2023
Victoria I. Bunik, Vasily A. Aleshin
core   +1 more source