Results 1 to 10 of about 86,313,599 (295)

Contribution of vitamin B 6 deficiency to anemia in children on regular hemodialysis [PDF]

BMC Pediatrics
Background Anemia is prevalent among pediatric patients diagnosed with end-stage kidney disease (ESKD). In addition, erythropoiesis-stimulating agents (ESA) and iron supplementation are considered the cornerstones in the management of anemia.
Fatma Atia, Hafez Bazaraa, Yara Abdelatty, Sarah Lotfy, Eman Eryan   +4 more
doaj   +2 more sources

Effects of Pelleting and Long-Term High-Temperature Stabilization on Vitamin Retention in Swine Feed

Animals, 2022
The objective of this study was to study the effect of pelleting and long-term high-temperature stabilization on the retention of vitamin A, vitamin E, vitamin B2, and vitamin B6 in swine feed. Piglet diets (diet 1 and 3) were pelleted after conditioning
Huakai Wang, Longxian Li, Nan Zhang, Tuan Zhang, Yongxi Ma   +4 more
doaj   +1 more source

Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects. [PDF]

PLoS ONE, 2013
Marginal deficiency of vitamin B-6 is common among segments of the population worldwide. Because pyridoxal 5'-phosphate (PLP) serves as a coenzyme in the metabolism of amino acids, carbohydrates, organic acids, and neurotransmitters, as well as in ...
Jesse F Gregory, Youngja Park, Yvonne Lamers, Nirmalya Bandyopadhyay, Yueh-Yun Chi, Kichen Lee, Steven Kim, Vanessa da Silva, Nikolas Hove, Sanjay Ranka, Tamer Kahveci, Keith E Muller, Robert D Stevens, Christopher B Newgard, Peter W Stacpoole, Dean P Jones   +15 more
doaj   +1 more source

Therapeutic Potential of a Novel Vitamin D₃ Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

Biomolecules, 2022
The regulation of vitamin D3 actions in humans occurs mainly through the Cytochrome P450 24-hydroxylase (CYP24A1) enzyme activity. CYP24A1 hydroxylates both 25-hydroxycholecalciferol (25(OH)D3) and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), which is ...
Ali K. Alshabrawy, Yingjie Cui, Cyan Sylvester, Dongqing Yang, Emilio S. Petito, Kate R. Barratt, Rebecca K. Sawyer, Jessica K. Heatlie, Ruhi Polara, Matthew J. Sykes, Gerald J. Atkins, Shane M. Hickey, Michael D. Wiese, Andrea M. Stringer, Zhaopeng Liu, Paul H. Anderson   +15 more
doaj   +1 more source

Polyneuropathy monitoring in Parkinson's disease patients treated with levodopa/carbidopa intestinal gel

Brain and Behavior, 2021
Objectives Levodopa‐carbidopa‐intestinal‐gel (LCIG) infusion is an effective treatment for advanced PD with motor fluctuations. Polyneuropathy occurs as a complication in 10–15% of patients.
K. Amande M. Pauls, Jussi Toppila, Maija Koivu, Johanna Eerola‐Rautio, Marianne Udd, Eero Pekkonen   +5 more
doaj   +1 more source

B-Vitamins and Choline in Human Milk Are Not Impacted by a Preconception Lipid-Based Nutrient Supplement, but Differ Among Three Low-to-Middle Income Settings—Findings From the Women First Trial

Frontiers in Nutrition, 2021
Introduction: Optimal human milk (HM) B-vitamin concentrations remain undefined, especially in areas where undernutrition is prevalent. The impact of supplementation pre-conception through pregnancy on HM B-vitamin composition remains unknown.Methods ...
Bridget E. Young, Jamie Westcott, Jennifer Kemp, Lindsay Allen, Lindsay Allen, Daniela Hampel, Daniela Hampel, Ana L. Garcés, Lester Figueroa, Shivaprasad S. Goudar, Sangappa M. Dhaded, Manjunath Somannavar, Sarah Saleem, Sumera Aziz Ali, K. Michael Hambidge, Nancy F. Krebs, The Women First Working Group, Veena Herekar, Sunil S Vernekar, S Yogeshkumar, Umber Khan, Farina Abrejo, Robert K Goldenberg, Richard J Derman, Beth McClure   +24 more
doaj   +1 more source

One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus [PDF]

Diabetes & Metabolism Journal
Diabetes mellitus (DM) affects about 9.3% of the population globally. Hyperhomocysteinemia (HHcy) has been implicated in the pathogenesis of DM, owing to its promotion of oxidative stress, β-cell dysfunction, and insulin resistance.
Jie Zhu, Gunjana Saikia, Xiaotao Zhang, Xiaoxi Shen, Ka Kahe   +4 more
doaj   +1 more source

Time out: should vitamin D dosing be based on patient's body mass index (BMI): a prospective controlled study

Journal of Nutritional Science, 2021
The recommended daily dose of vitamin D is 2000 IU was found to be insufficient in many patients. The objective of the present study is to find whether the daily dose of vitamin D should be based on BMI.
Mir Sadat-Ali, Khalid W. AlTabash, Haifa A. Al-Turki, Sulaiman A. AlMousa, Hasan N. AlSayed   +4 more
doaj   +1 more source

Genetically Predicted Circulating Concentrations of Micronutrients and COVID-19 Susceptibility and Severity: A Mendelian Randomization Study

Frontiers in Nutrition, 2022
BackgroundCoronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which since 2019 has caused over 5 million deaths to date.
Neil Daniel, Emmanouil Bouras, Konstantinos K. Tsilidis, Konstantinos K. Tsilidis, David J. Hughes   +4 more
doaj   +1 more source

Vitamin B complex and vitamin B 12 levels after peripheral nerve injury

Neural Regeneration Research, 2016
The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B 12 were altered after crush-induced peripheral nerve injury in an experimental rat model.
Idiris Altun, Ergül Belge Kurutaş
doaj   +1 more source