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Vitamin B-6 [PDF]

Advances in Nutrition, 2015
Vitamin B-6 is a water-soluble vitamin first discovered as a factor that cured dermatitis in rats. There are 6 forms of vitamin B-6 found in mammals. The naturally occurring forms of the vitamin include pyridoxine (PN), pyridoxal (PL), pyridoxamine (PM), and their respective monophosphorylated derivatives (PNP, PLP, and PMP).
Patrick J, Stover, Martha S, Field
openaire   +3 more sources

Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial [PDF]

Trials, 2012
Background Vitamin A supplementation of 6-59 month old children is currently recommended by the World Health Organization based on evidence that it reduces mortality.
Bahl Rajiv, Bhandari Nita, Dube Brinda, Edmond Karen, Fawzi Wafaie, Fontaine Olivier, Kaur Jasmine, Kirkwood Betty R, Martines Jose, Masanja Honorati, Mazumder Sarmila, Msham Salum, Newton Sam, Oleary Maureen, Ruben Julia, Shannon Caitlin, Smith Emily, Taneja Sunita, Yoshida Sachiyo   +18 more
doaj   +2 more sources

Vitamin B-6 Metabolism and Interactions with TNAP

, 2015
Two observations stimulated the interest in vitamin B-6 and alkaline phosphatase in brain: the marked increase in plasma pyridoxal phosphate and the occurrence of pyridoxine responsive seizures in hypophosphatasia. The increase in plasma pyridoxal phosphate indicates the importance of tissue non-specific alkaline phosphatase (TNAP) in transferring ...
Stephen P. Coburn, Coburn, Stephen P.
openaire   +4 more sources

Effects of Pelleting and Long-Term High-Temperature Stabilization on Vitamin Retention in Swine Feed

Animals, 2022
The objective of this study was to study the effect of pelleting and long-term high-temperature stabilization on the retention of vitamin A, vitamin E, vitamin B2, and vitamin B6 in swine feed. Piglet diets (diet 1 and 3) were pelleted after conditioning
Huakai Wang, Longxian Li, Nan Zhang, Tuan Zhang, Yongxi Ma   +4 more
doaj   +1 more source

Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects. [PDF]

PLoS ONE, 2013
Marginal deficiency of vitamin B-6 is common among segments of the population worldwide. Because pyridoxal 5'-phosphate (PLP) serves as a coenzyme in the metabolism of amino acids, carbohydrates, organic acids, and neurotransmitters, as well as in ...
Jesse F Gregory, Youngja Park, Yvonne Lamers, Nirmalya Bandyopadhyay, Yueh-Yun Chi, Kichen Lee, Steven Kim, Vanessa da Silva, Nikolas Hove, Sanjay Ranka, Tamer Kahveci, Keith E Muller, Robert D Stevens, Christopher B Newgard, Peter W Stacpoole, Dean P Jones   +15 more
doaj   +1 more source

Therapeutic Potential of a Novel Vitamin D₃ Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

Biomolecules, 2022
The regulation of vitamin D3 actions in humans occurs mainly through the Cytochrome P450 24-hydroxylase (CYP24A1) enzyme activity. CYP24A1 hydroxylates both 25-hydroxycholecalciferol (25(OH)D3) and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), which is ...
Ali K. Alshabrawy, Yingjie Cui, Cyan Sylvester, Dongqing Yang, Emilio S. Petito, Kate R. Barratt, Rebecca K. Sawyer, Jessica K. Heatlie, Ruhi Polara, Matthew J. Sykes, Gerald J. Atkins, Shane M. Hickey, Michael D. Wiese, Andrea M. Stringer, Zhaopeng Liu, Paul H. Anderson   +15 more
doaj   +1 more source

Natural Variation in Vitamin B(1) and Vitamin B(6) Contents in Rice Germplasm. [PDF]

, 2022
peer reviewedInsufficient dietary intake of micronutrients contributes to the onset of deficiencies termed hidden hunger-a global health problem affecting approximately 2 billion people.
Mangel, Nathalie, Fitzpatrick, Thérésa Bridget, Gruissem, Wilhelm, Fitzpatrick, Teresa B., Fudge, Jared, Vanderschuren, Hervé, Fudge, Jared B., Fudge, Jared B, Fitzpatrick, Teresa B   +8 more
core   +1 more source

Cutaneous Metabolism of Vitamin B-6 [PDF]

Journal of Investigative Dermatology, 2003
Vitamin B-6 is important for skin development and maintenance. We examined vitamin B-6 metabolism in human and mouse skin collected at different phases of the hair cycle; in hamster melanomas; in normal and immortalized human keratinocytes (HaCaT) and several human melanoma cell lines.
Coburn, Stephen P., Slominski, Andrzej, Dennis Mahuren, J., Wortsman, Jacobo, Hessle, Lovisa, Millan, Jose Luis   +5 more
openaire   +2 more sources

Polyneuropathy monitoring in Parkinson's disease patients treated with levodopa/carbidopa intestinal gel

Brain and Behavior, 2021
Objectives Levodopa‐carbidopa‐intestinal‐gel (LCIG) infusion is an effective treatment for advanced PD with motor fluctuations. Polyneuropathy occurs as a complication in 10–15% of patients.
K. Amande M. Pauls, Jussi Toppila, Maija Koivu, Johanna Eerola‐Rautio, Marianne Udd, Eero Pekkonen   +5 more
doaj   +1 more source

B-Vitamins and Choline in Human Milk Are Not Impacted by a Preconception Lipid-Based Nutrient Supplement, but Differ Among Three Low-to-Middle Income Settings—Findings From the Women First Trial

Frontiers in Nutrition, 2021
Introduction: Optimal human milk (HM) B-vitamin concentrations remain undefined, especially in areas where undernutrition is prevalent. The impact of supplementation pre-conception through pregnancy on HM B-vitamin composition remains unknown.Methods ...
Bridget E. Young, Jamie Westcott, Jennifer Kemp, Lindsay Allen, Lindsay Allen, Daniela Hampel, Daniela Hampel, Ana L. Garcés, Lester Figueroa, Shivaprasad S. Goudar, Sangappa M. Dhaded, Manjunath Somannavar, Sarah Saleem, Sumera Aziz Ali, K. Michael Hambidge, Nancy F. Krebs, The Women First Working Group, Veena Herekar, Sunil S Vernekar, S Yogeshkumar, Umber Khan, Farina Abrejo, Robert K Goldenberg, Richard J Derman, Beth McClure   +24 more
doaj   +1 more source