Results 121 to 130 of about 76,997 (309)
Advanced Science, EarlyView.A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li +14 more
wiley +1 more source
AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
Advanced Science, EarlyView.This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
Catalogue de la troisième exposition du Salon des Cent dans les Galeries de la Plume.
Text by Léon Maillard.Mode of access ...
Salon des cent (3rd) +2 more
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Advanced Science, EarlyView.Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
, 1983 14 p. transcript of an interview with Laurie Plume conducted by Christine Welsh and Tony Snowsill on February 15, 1983. Tape number IH-008,Side B/IH-009 transcript disc 6.NOTE: This transcript is a very rough English translation of an interview conducted
Plume, Laurie +2 more
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Data for: Build it and they will come: The convening power of the SOLEIL Synchrotron facility
Data supporting the ICSR Perspectives paper: Build it and they will come: The convening power of the SOLEIL Synchrotron ...
Plume, A
core +1 more source
A model for large-scale volcanic plumes on Io: Implications for eruption rates and interactions between magmas and near-surface volatiles. [PDF]
, 2002 Volcanic plumes deposit magmatic pyroclasts and SO2 frost on the surface of Io. We model the plume activity detected by Galileo at the Pillan and Pele sites from 1996 to 1997 assuming that magmatic eruptions incorporate liquid SO2 from near-surface ...
Gilbert, Jennie +3 more
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Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
A Review of Failure Modes and Safety Strategies of Lithium‐Ion Batteries from Materials to Systems
Advanced Science, EarlyView.A cascade‐aware framework is presented for lithium‐ion battery safety, linking thermal runaway initiation, acceleration, runaway reaction, and propagation with material‐, cell/pack‐, and system‐level interventions. By integrating failure mechanisms, quantitative safety indicators, and staged interception strategies, this review highlights how safer ...
Jin Hyeok Yang +8 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source