Results 91 to 100 of about 351,618 (311)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The criterion of individuation in the philosophy of Aristotle: Form or Matter? [PDF]
حکمت و فلسفه, 2015 The discussion of the criterion of individuation has been an important and complex metaphysical debate in the history of philosophy and this is related with what its presence makes us to reach from the general or universal person to the fiddling person ...
mojtaba derayati
doaj
Tip cap for a rotor blade [PDF]
, 1983 A replaceable tip cap for attachment to the end of a rotor blade is described. The tip cap includes a plurality of walls defining a compartment which, if desired, can be divided into a plurality of subcompartments.
Gay, C. H., Jr. +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Role of the plurality rule in multiple choices
, 2016 People are often challenged to select one among several alternatives. This situation is present not only in decisions about complex issues, e.g., political or academic choices, but also about trivial ones, as in daily purchases at a supermarket.
Anteneodo, Celia +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2017 A CCD image sensor of the type for providing charge multiplication by impact ionisation has an image area and a plurality of pixels. A separate multiplication register has a plurality of multiplication elements arranged to receive charge from the pixels ...
Jerram, Paul, Stefanov, Konstantin
core
Estado plural, indios plurales
REVISTA TRACE, 2018 De los antropólogos de los años sesenta heredamos una visión de comunidad indígena cerrada, estable, homogénea y monolítica, que tuve la ocasión de criticar en otro sitio (Dehouve, 2001b y 2003). Pero no basta con desconstruir la noción de comunidad, también es necesario reconsiderar la de Estado, que va de la mano, pues los defensores de esta teoría ...
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source