Results 101 to 110 of about 69,541 (306)

Éloge du lisible (sur S/Z)

open access: yesCarnets, 2016
This paper proposes a rereading of Barthes’ notion of readerly, defined in 1970, in S/Z. The purpose will be to analyze its birth, resorting to the notes from the seminar on Sarrasine, held by Barthes in the École pratique des hautes études from 1967 to ...
Andrea Del Lungo
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

An Overview Across the New Political Economy Literature [PDF]

open access: yes
This work presents a review of the literature on political process formation and the role of institutions on economic development. Models of citizen candidacy and candidate choice and equilibria under plurality rule elections are illustrated.
Luca Murrau
core  

Teologi Trauma Berbasis Budaya Orang Basudara Bagi Korban Konflik Komunal

open access: yesDunamis: Jurnal Teologi dan Pendidikan Kristiani
. The conflict that occurred in Ambon in 1999 between Christians and Muslims still left deep trauma for the people in the city of Ambon, especially for members of the congregation at the Church X.
Marfan Ferdinanda Tahamata   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Faster Algorithms for Computing Plurality Points [PDF]

open access: yes, 2016
Let V be a set of n points in R^d, which we call voters, where d is a fixed constant. A point p in R^d is preferred over another point p' in R^d by a voter v in V if dist(v,p) < dist(v,p').
Gudmundsson, Joachim   +2 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

The Importance of the Electoral Rule: Evidence from Italy [PDF]

open access: yes
We employ bootstrap methods (Efron (1979)) to test the effect of an important electoral reform implemented in Italy from 1993 to 2001, that moved the system for electing the Par-liament from purely proportional to plurality rule (for 75% of the seats ...
Massimo Bordignon, Andrea Monticini
core  

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