Results 151 to 160 of about 69,541 (306)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Comparing Methods for Attributing Hospital Quality Metrics to Individual Physicians: Impact on Performance Assessment and Outlier Identification. [PDF]

J Gen Intern Med
Carmichael HL, Woller SC, Brown SM, Asch SM, Srivastava R, Pirozzi M, Peltan ID.   +6 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Infertility treatment and the growth of children from birth to 12 years of age: A national cohort study. [PDF]

PLoS One
Chang YS, Yu T, Wong TJ, Li CY.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A weighted-voting electoral system that performs quite well. [PDF]

The paper describes a weighted-voting system for the election of a Parliament. The system is easy to implement, and it dominates plurality, where "dominates" means that it performs better with reference to both representativeness and stability.
Guido Ortona
core  

Demographic, birth, parental characteristics, and the risk of early-onset colorectal cancer: A population-based nested case-control study in California. [PDF]

Cancer
Siddique S, Wang R, Berardi D, Johnson CH, Wiemels JL, Metayer C, Ma X.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Understanding Plurality, Engagement, and Change in Vocational Education and Training through French Pragmatic Theory [PDF]

This paper argues for the use of French pragmatic theory for theorising about vocational education and training (VET) through a focus on understanding plurality, human engagement, and change within VET organisations and in various training situations and
Smeplass, E., Schmees, J., Hausgeth, J. F.   +2 more
core  

Coordinating innovation without unified authority: leadership and organizational identification in hybrid organizations. [PDF]

Front Psychol
Fu Y, Zhong YH, Agudamu, Zhang WL.
europepmc   +1 more source