Results 91 to 100 of about 173,543 (315)

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Pluripotent Stem Cells as a Model for Human Embryogenesis

, 2023
Pluripotent stem cells (PSCs; embryonic stem cells and induced pluripotent stem cells) can recapitulate critical aspects of the early stages of embryonic development; therefore, they became a powerful tool for the in vitro study of molecular mechanisms ...
Mikel Ángel Gidi-Grenat, Alejandro Martínez-Juárez, Néstor Fabián Díaz, Anayansi Molina-Hernández, Guadalupe García-López, Wendy Portillo, Néstor Emmanuel Díaz-Martínez, Daniela Ávila-González   +7 more
core   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Effects of reprogramming on genomic imprinting and the application of pluripotent stem cells

Stem Cell Research, 2019
Pluripotent stem cells are considered to be the ideal candidates for cell-based therapies in humans. In this regard, both nuclear transfer embryonic stem (ntES) cells and induced pluripotent stem (iPS) cells are particularly advantageous because patient ...
Xiajun Li, Max Jiahua Li, Yang Yang, Yun Bai   +3 more
doaj   +1 more source

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source

Efficient induction of EPSCs via episomal reprogramming: a functionally equivalent yet transcriptionally specialized alternative to EPSCs

Stem Cell Research
This study establishes a streamlined one-step strategy using optimized episomal plasmid reprogramming to directly generate extended pluripotent stem cells (dEPSCs) from human peripheral blood mononuclear cells (PBMCs), bypassing the induced pluripotent ...
Ran Zheng, Mengna Zhang, Yanhong Cheng, Junjie Wen, Xiyu Zhao, Dan Xiao, Jingyu Xu, Ke Pei, Liang Wang, Jie Xu, Jian Zhang, Cheguo Cai, Yunfeng Gao   +12 more
doaj   +1 more source

Reprogramming of Mouse Calvarial Osteoblasts into Induced Pluripotent Stem Cells [PDF]

, 2018
Previous studies have demonstrated the ability of reprogramming endochondral bone into induced pluripotent stem (iPS) cells, but whether similar phenomenon occurs in intramembranous bone remains to be determined.
Wang, Y, Sham, MH, Cheung, MCH, Leung, KKH, Chan, D, Liu, AJ, Cheah, KSE   +6 more
core   +1 more source

Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells

, 2022
Art. 417865Embryonic and induced pluripotent stem cells (IPSCs) derived from mammalian species are valuable tools for modeling human disease, including retinal degenerative eye diseases that result in visual loss.
Yang, J., Liew, C.G., Torrez, L.B., Klassen, H., Perez, Y., Nieden, N.I. zur   +5 more
core   +1 more source

Soft, Degradable, and Magnetic Microcarriers for Encapsulation and Guided Transport of Drugs and 3D Spheroids

Advanced Materials, EarlyView.
This work presents soft, degradable hydrogel microcarriers that combine magnetic responsiveness with the ability to host multiple therapeutic and cellular components. Produced by droplet microfluidics, the carriers maintain structural integrity during manipulation, permit controlled breakdown under physiological conditions, and enable guided motion for
Xuan Peng, Lulu Song, Daryna Mruga, Veronika Bakhmat, Sergei Dzyadevych, Lin Guo, Shahrukh Shakeel, Rico Illing, Olha Bezsmertna, Xiaotao Wang, Nicholas R. Posselli, Sarthak Misra, Sandra Hauser, Jens Pietzsch, Klaus Kopka, Denys Makarov, Željko Janićijević, Xinne Zhao, Larysa Baraban   +18 more
wiley   +1 more source

Comprehensive insight into chicken germline cells: A review

Poultry Science
Genetic information is propagated in the progeny through germ cells. The stem cells which are precursors of these germ cells have the ability of self-renewal and can give rise to pluripotent stem cells under favorable conditions.
Malik Ahsan Ali, Kai Jin, Guohong Chen, Xiaomeng Pei, Bichun Li   +4 more
doaj   +1 more source