Results 161 to 170 of about 151,183 (283)

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq   +2 more
wiley   +1 more source

Assessing Moisture Content of Coolstored Blueberries During Water Loss Scenarios Using Hyperspectral Imaging

open access: yesNew Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 2, June 2026.
Water loss is a key factor affecting the postharvest quality and shelf life of blueberries, and storage conditions (humidity and time) play an important role in regulating water retention capacity of stored berries. This study aims to explore the variation of moisture content (MC) in blueberries under different storage humidity and storage time ...
RunKai Wang   +3 more
wiley   +1 more source

Rhamnogalacturonan‐II Dimerisation Reinforces Salt Resistance in Sugar Beet

open access: yesPlant, Cell &Environment, Volume 49, Issue 6, Page 3082-3100, June 2026.
ABSTRACT Salinity stress predominantly affects negatively charged cell wall polymers, for example, pectin. Excess Na+ ions interact physically and affect growth in stress‐sensitive plants. However, the salinity resistance of sugar beet cell walls remains unclear.
Shah Newaz Chowdhury   +5 more
wiley   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

open access: yesChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga   +11 more
wiley   +1 more source

PME framework

open access: yes
A planning and guidance document outlining the relationship between the project activities, targets, deliverables, milestones and intended strategic impact, in the framework of the project time period, as well as description of how and when progress will be measured.
openaire   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui   +8 more
wiley   +1 more source

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