Results 191 to 200 of about 151,183 (283)

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

Acta Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami, Domenico Marson, Eiki Yamashita, Bruno Broshka, Ui Okada, Maho Aoki, Giannamaria Annunziato, Erik Laurini, Emanuele Carosati, Marco Pieroni   +9 more
wiley   +1 more source

ALKB-1-dependent tRNA methylation is required for efficient paternal mitochondrial elimination. [PDF]

Nat Commun
Luo Z, Li Y, He C, Wu D, Dai W, Hu L, Yang J, Harry BL, Ju Z, Tavernarakis N, Wang H, Wan QL, Zhou Q.   +12 more
europepmc   +1 more source

School‐based induction for newly qualified teachers in classroom and special education teaching roles: How school‐based induction supports inclusive and special education teaching practices

Support for Learning, Volume 41, Issue 2, May 2026.
Abstract This article explores how school‐based induction supported Newly Qualified Teachers (NQTs) to develop inclusive teaching practices in a mainstream primary school in Ireland. Focusing on an NQT in a mainstream class and an NQT in a Special Education Teacher (SET) role, the study examines how structured reflective dialogue, collaborative ...
Lisa Clinton, Ann Marie Farrell
wiley   +1 more source

Dual Chain-Mediation of GenAI Chatbots on Loneliness: Perceived Misinformation Exposure and User Trust via Negative Emotions. [PDF]

Int J Public Health
Wang Y, Xu C.
europepmc   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, Volume 183, Issue 9, Page 1993-2008, May 2026.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

A Certificação PME

, 2019
Small and medium-sized enterprises represent most of the European and Portuguese business fabric and are fundamental for the development of the economy. Due to their size and frequent scarcity of resources, they need adequate public policies that promote their activity, enhancing their contribution to sustainability and inclusive growth, to the ...
openaire   +1 more source

Patients' experiences of participating in a nurse‐led clinic for bowel dysfunction following rectal cancer: A qualitative interview study

Colorectal Disease, Volume 28, Issue 5, May 2026.
Abstract Background An increasing number of patients survive rectal cancer, leading to a rise in the number of patients with late sequelae following surgical and oncological treatments. Consequently, the demand for information, treatment and counselling among these patients is on the rise. Nurse‐led clinics, staffed by nurses with specialised expertise
Birgitte Schantz Laursen, Gitte Kjær Sørensen, Margit Majgaard, Karen Irene Jacobsen, Helle Vindfeldt Rasmussen, Mathilde Grosell, Therese Juul, Peter Christensen, Marianne Krogsgaard   +8 more
wiley   +1 more source

La PME tunisienne

, 2022
Denieuil, Pierre-Noël, Denieuil, Pierre-Noël > Auteur, B'chir, Abdelkhalek > Auteur   +2 more
openaire   +1 more source

Where We're Going, We Won't Need Eyes to See: Distributional Range Size Drivers of European Subterranean Spiders

Journal of Biogeography, Volume 53, Issue 5, May 2026.
ABSTRACT Aim Understanding why closely related species can have drastically different distributional range sizes is a fundamental question in biology. However, answering this question is challenging due to the multiple inter‐related factors that shape species distributions, particularly in continental regions, where unclear ecological and geographic ...
Adrià Bellvert, Giuseppe Nicolosi, Martina Pavlek, Lorenzo Cresi, Stefano Mammola   +4 more
wiley   +1 more source

One new species of <i>Drapetisca</i> Menge, 1866 (Araneae, Linyphiidae) from Gele Mountain, Chongqing, China. [PDF]

Biodivers Data J
Shi HX, Liu ZY, Irfan M, Wang LY.
europepmc   +1 more source