Results 201 to 210 of about 151,183 (283)

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti‐Contractile Effect of Perivascular Adipose Tissue

open access: yesMicrocirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt   +9 more
wiley   +1 more source

Perceived Effectiveness of Cigar Warnings Among Young People in the United States. [PDF]

open access: yesAm J Prev Med
Ranney LM   +8 more
europepmc   +1 more source

Engineering of 10‐Deacetylbaccatin III‐10‐β‐O‐Acetyltransferase From Taxus Species for Efficient Acetylating Non‐Natural Substrates Into Taxol in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3308-3323, May 2026.
ABSTRACT 7‐β‐xylosyl‐10‐deacetyltaxol (XDT) is much more abundant than the anticancer drug Taxol in Taxus species and is usually regarded as the by‐product of Taxol. It could be enzymatically transformed into 10‐deacetyltaxol (DT), and the latter could be further converted into Taxol.
Tian‐Jiao Chen   +5 more
wiley   +1 more source

High Spin Iron–Phosphinidene and Arsinidene Complexes With Attenuated Metal–Ligand Multiple Bond Character

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Unusually low metal–ligand bond orders are observed in high spin iron(II) pnictogenidene (PH2– and AsH2–) complexes. Electronic structure analysis provides evidence for multiconfigurational character that attenuates the metal–ligand multiple bond character normally that is typically associated with pnictogenidene ligands. These complexes can be used to
Austin D. Chivington   +5 more
wiley   +2 more sources

Dissecting the Spectrum of Rare BRAF Mutations in Melanoma: A Nation‐Wide Study by the Italian Melanoma Intergroup (IMI)

open access: yesPigment Cell &Melanoma Research, Volume 39, Issue 3, May 2026.
In a large multicentre Italian cohort (14,081 melanoma cases from 19 centres), rare BRAF mutations (~2%) showed survival and response to targeted therapy comparable to V600E/K. Functional modeling indicates that variants, particularly near codon 600, can induce constitutive activation, supporting expanded BRAF genotyping to identify additional patients
Bruna Dalmasso   +50 more
wiley   +1 more source

Additive Manufacturing of Shape-Changing Printlets via Powder-Based Extrusion 3D Printing of Natural Cellulose and Polyvinyl Alcohol. [PDF]

open access: yesPolymers (Basel)
Dokhom K   +7 more
europepmc   +1 more source

Balancing Digital Transformation and Modernization: Pathways for Public Managers

open access: yesPublic Administration Review, Volume 86, Issue 3, Page 610-625, May/June 2026.
ABSTRACT This study examines the interplay between digital modernization and transformation in the public sector, challenging the notion that they are mutually exclusive strategies. Through interviews with public sector leaders, we find that modernization and transformation can be jointly implemented rather than managed as competing efforts.
Marc E. B. Picavet   +4 more
wiley   +1 more source

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