Results 31 to 40 of about 151,183 (283)

Paramagnetic Meissner effect in superconductors from self-consistent solutions of Ginzburg-Landau equations

open access: yes, 2000
The paramagnetic Meissner effect (PME) is observed in small superconducting samples, and a number of controversial explanations of this effect are proposed, but there is as yet no clear understanding of its nature.
A. Bezryadin   +19 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Clinical phenotype features and genetic etiologies of 38 children with progressive myoclonic epilepsy

open access: yesActa Epileptologica, 2020
Background Progressive myoclonic epilepsy (PME) is a group of neurodegenerative diseases with genetic heterogeneity and phenotypic similarities, and many cases remain unknown of the genetic causes. This study is aim to summarize the clinical features and
Jing Zhang   +16 more
doaj   +1 more source

PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling

open access: yesCell Death Discovery, 2023
Glioblastoma (GBM) is the most common primary brain tumor in adults. Current standard therapy is surgery followed by radiotherapy, with concurrent and adjuvant temozolomide chemotherapy.
Liesbeth Guffens   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

PME allemandes [PDF]

open access: yes, 2010
Les PME industrielles allemandes sont une référence mondiale pour la qualité du made in Germany. Et elles ont la réputation de sortir gagnantes des grands défis contemporains : tertiarisation, globalisation des activités et même récession brutale dans la crise de la finance mondiale de 2008.
openaire   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Curvature‐Tuned Friction at Electrified Ionic Liquid Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
Graphene curvature plays a key role in friction electrotunability at single‐asperity contacts lubricated by ionic liquids. A 9 nm radius yields stronger tunability than larger radii, with distinct friction coefficients at low and high loads indicating a shift in the slippage plane.
Wei Song   +6 more
wiley   +1 more source

LES INNOVATIONS MANAGÉRIALES ENTRE LE BESOIN D’ACCOMPLISSEMENT PERSONNEL ET L’AVERSION AU RISQUE DU DIRIGEANT-PROPRIÉTAIRE : CAS DES PME FAMILIALES DE LA VILLE D’AGADIR

open access: yesRevue Internationale du Marketing et Management Stratégique, 2021
Les entreprises de toutes tailles se concentrent sur la recherche de ressources pour créer et maintenir des avantages concurrentiels. Le profil psychologique est donc une ressource stratégique qui permet aux PME d'établir un avantage concurrentiel ...
AYOUB EL ABIDI, MOHAMED BINKKOUR
doaj  

Engineering Intelligent Graphene Oxide‐Cellulose Membranes: Suppressing Thermal Runaway for a Safer Aqueous Zinc‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
A novel thermos‐responsive hydroxypropyl cellulose/graphene oxide (HPC/GO) composite membrane is fabricated for reversible temperature‐gated ion transport in aqueous zinc‐ion batteries. Enabled by LCST‐driven structural transition, unimpeded ion diffusion at room temperature delivers high capacity, while elevated temperature suppresses transport; full ...
Xueli Bi   +9 more
wiley   +1 more source

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