Results 41 to 50 of about 74,938 (343)

Joining the meta-research movement: A bibliometric case study of the journal Perspectives on Medical Education

Perspectives on Medical Education, 2022
Purpose To conduct a bibliometric case study of the journal Perspectives on Medical Education (PME) to provide insights into the journal’s inner workings and to “take stock” of where PME is today, where it has been, and where it might go.
Lauren A. Maggio, Stefanie Haustein, Joseph A. Costello, Erik W. Driessen Driessen, Anthony R. Artino   +4 more
doaj   +1 more source

PME et Territoire

, 2020
L’entreprise est l’acteur opérationnel du développement, c’est le cas plus particulièrement de la PME qui constitue l’épine dorsale de toute économie. La naissance et la croissance de cette catégorie d’entreprise sont largement dépendantes de son territoire d’implantation, une dépendance qui résulte de la relation interactive entre les différents ...
JAFARI Maria, BENTHAMI Asmae
openaire   +2 more sources

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Pectin methylesterase activity determined by different methods and thermal inactivation of exogenous pme in mango juice Determinação da atividade da pectina metilesterase por diferentes métodos e inativação térmica da PME exógena no suco de manga

Ciência e Agrotecnologia, 2011
Pectin methylesterase (PME) hydrolyzes methyl ester groups in pectin chains to form carboxylic groups, releasing methanol and H3O+. The aim of this study was to determine PME activity in samples of pectinases by UV-VIS spectroscopy, to measure the acid ...
Samantha Lemke Gonzalez, Regina Cristina Aparecida Lima, Eliana Beleski Borba Carneiro, Mareci Mendes de Almeida, Neiva Deliberali Rosso   +4 more
doaj   +1 more source

“Something’s Happening Here!”: Popular Music Education in the United States [PDF]

IASPM Journal, 2015
Although the number of opportunities to learn popular music in the United States continues to grow, popular music education (PME) programs remain exceptional at primary, secondary, and tertiary levels of institutionalized music education.
Bryan Powell, Andrew Krikun, Joseph Michael Pignato   +2 more
doaj   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Communication interne comme outil stratégique de performance organisationnelle des PME de Kinshasa: une analyse quantitative [PDF]

Mouvements et Enjeux Sociaux
Cet article examine dans quelle mesure la communication interne constitue un outil stratégique pour améliorer la performance organisationnelle des PME de Kinshasa.
Gédéon MIASSA, Héraclès KABWASA, Chancelier MUYENE NESTOR   +2 more
doaj  

Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation.

PLoS ONE, 2015
Protein phosphatase 2A (PP2A) is a conserved essential enzyme that is implicated as a tumor suppressor based on its central role in phosphorylation-dependent signaling pathways.
Ryotaro Yabe, Akane Miura, Tatsuya Usui, Ingrid Mudrak, Egon Ogris, Takashi Ohama, Koichi Sato   +6 more
doaj   +1 more source