Results 21 to 30 of about 11,444 (233)

Uma visão do VI Congresso Brasileiro de Gerenciamento de Projetos

Navus: Revista de Gestão e Tecnologia, 2012
Este trabalho relata uma visão do VI CONGRESSO BRASILEIRO DE GERENCIAMENTO DE PROJETOS & III FÓRUM INTERNACIONAL DE GOVERNO, destacando os pontos principais dos assuntos debatidos.
Helio Aisenberg Ferenhof
doaj   +1 more source

Enhanced anti-glioma efficacy of biodegradable periodic mesoporous organosilica nanoparticles through target delivery of chemotherapeutics

Journal of Materials Science: Materials in Medicine, 2023
Glioma is the most common malignant tumor of the brain and enhancing the efficacy of chemotherapy in glioma is critical for improving patients’ prognosis.
Min Dong, Ying Liu, Biao Liu, Jin Peng, Yuxia Tang, Guangming Lu, Haibin Shi, Feipeng Zhu   +7 more
doaj   +1 more source

Inverse Vulcanization Through Epoxide Chemistry: A Low Temperature Non‐Olefin Route to Sulfur‐Rich Polymer Networks

Angewandte Chemie, EarlyView.
Epoxide monomers undergo base‐catalyzed ring‐opening copolymerization with elemental sulfur to afford sulfur‐rich polymers under mild conditions. The resulting materials exhibit excellent mechanical performance, strong adhesion (up to 10 MPa on stainless steel), and outstanding reprocessability.
Pan Yang, Youfu Wang, Xinyuan Zhu, Jinhong Jia, Xiaofeng Wu, Tom Hasell   +5 more
wiley   +2 more sources

Barriers to Effective Postmenopausal Osteoporosis Treatment: A Qualitative Study of Patients' and Practitioners' Views. [PDF]

PLoS ONE, 2016
Only a minority of patients at high risk for osteoporotic fracture receive treatment.Study patients' and physicians' views regarding postmenopausal osteoporosis (PMO) to identify impediments to good care.A qualitative study involving 18 physicians and 37
Sophie Alami, Lucile Hervouet, Serge Poiraudeau, Karine Briot, Christian Roux   +4 more
doaj   +1 more source

Validation of revised patient measures of safety: PMOS-30 and PMOS-10 [PDF]

BMJ Open, 2019
Objectives There is growing evidence that patients can provide feedback on the safety of their care. The 44-item Patient Measure of Safety (PMOS) was developed for this purpose. While valid and reliable, the length of this questionnaire makes it potentially challenging for routine use. Our study aimed to produce
Gemma Louch, Caroline Reynolds, Sally Moore, Claire Marsh, Jane Heyhoe, Abigail Albutt, Rebecca Lawton   +6 more
openaire   +3 more sources

PMO as Change Agent [PDF]

, 2020
A Project Management Office ("PMO") is an agent for change in furtherance of strategy. This paper will discuss how change was created by a PMO and how that same change ultimately reshaped the PMO itself.
Brian M Horgan
core  

Targeting ferroptosis by poly(acrylic) acid coated Mn3O4 nanoparticles alleviates acute liver injury

Nature Communications, 2023
Ferroptosis, a newly characterized form of regulated cell death, is induced by excessive accumulation of lipid peroxidation catalyzed by intracellular bioactive iron.
Xinyi Shan, Jiahuan Li, Jiahao Liu, Baoli Feng, Ting Zhang, Qian Liu, Huixin Ma, Honghong Wu, Hao Wu   +8 more
doaj   +1 more source

Tween 85-Modified Low Molecular Weight PEI Enhances Exon-Skipping of Antisense Morpholino Oligomer In Vitro and in mdx Mice

Molecular Therapy: Nucleic Acids, 2017
We investigated a series of Tween 85 modified low molecular weight polyethylenimine (LPEI, 0.8k/1.2k/2.0k)-copolymers (Zs) through simple formulation and covalent conjugation with phosphorodiamidate morpholino oligomer (PMO) for their potential to ...
Mingxing Wang, Bo Wu, Jason D. Tucker, Sapana N. Shah, Peijuan Lu, Lauren E. Bollinger, Qilong Lu   +6 more
doaj   +1 more source

Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice

Drug Delivery, 2017
Antisense oligonucleotide therapy for Duchenne muscular dystrophy has shown great potential in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery.
Mingxing Wang, Bo Wu, Sapana N Shah, Peijuan Lu, Qilong Lu   +4 more
doaj   +1 more source

Aminoglycoside Enhances the Delivery of Antisense Morpholino Oligonucleotides In Vitro and in mdx Mice

Molecular Therapy: Nucleic Acids, 2019
Antisense oligonucleotide (AO) therapy has been the specific treatment for Duchenne muscular dystrophy, with ongoing clinical trials. However, therapeutic applications of AOs remain limited, particularly because of the lack of efficient cellular delivery
Mingxing Wang, Bo Wu, Sapana N. Shah, Peijuan Lu, Qilong Lu   +4 more
doaj   +1 more source