Results 31 to 40 of about 5,887 (204)

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

WGCNA Identification of Genes and Pathways Involved in the Pathogenesis of Postmenopausal Osteoporosis

International Journal of General Medicine, 2021
Meng-Lei Hao,1,* Xiao-Qin Zuo,2,* Yong Qiu,3,* Jian Li1 1Department of Endocrinology, Zigong First People’s Hospital, Zigong Academy of Medical Sciences, Zigong, Sichuan Province, People’s Republic of China; 2Department of Geriatric Medicine,
Hao ML, Zuo XQ, Qiu Y, Li J
doaj  

Multispectral UV Imaging on Capacitive CMOS Arrays Enabled by Solution‐Processed Metal‐Oxide Nanoparticles

Advanced Science, EarlyView.
Ultraviolet (UV) imagers are important for a variety of applications but often require dedicated semiconductor process flows. Here, a versatile capacitive CMOS platform is transformed into a visible‐blind, multispectral UV imager through post‐CMOS functionalization with solution‐processed metal‐oxide nanoparticles. The UV‐induced photodielectric effect
Suman Kundu, Tao Shen, Kai Betlem, Murali K. Ghatkesar, Peter G. Steeneken, Frans P. Widdershoven   +5 more
wiley   +1 more source

Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice

Drug Delivery, 2017
Antisense oligonucleotide therapy for Duchenne muscular dystrophy has shown great potential in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery.
Mingxing Wang, Bo Wu, Sapana N Shah, Peijuan Lu, Qilong Lu   +4 more
doaj   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

Advanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

HUBUNGAN KEBERADAAN PENGAWAS MENELAN OBAT DENGAN KEPATUHAN MINUM OBAT PASIEN TUBERKULOSIS DI PUSKESMAS CIMAHI SELATAN KOTA CIMAHI

Jurnal Kesehatan Budi Luhur, 2023
Pada tahun 2020, 9,9 juta telah didiagnosis dengan tuberkulosis (TB) dan 1,5 juta tidak mendapat pengobatan TB Salah satu dari delapan negara yang memiliki kasus TB ke dua terbanyak di dunia adalah Indonesia.
Dwi Yulnovianti, Mochamad Ari Fardiansyah, Karwati   +2 more
doaj   +1 more source

Synchronization of Analog Neuron Circuits With Digital Memristive Synapses: An Hybrid Approach

Advanced Electronic Materials, EarlyView.
An hybrid circuit mimicking neural units coupled using memristive synapses is introduced. The analog neurons provide flexibility and robustness, and the digital memristive coupling guarantees the full reconfigurability of the interconnection. The onset of a synchronized spiking behavior in two circuits mimicking the Izhikevich neuron is discussed from ...
Lamberto Carnazza, Francesco Maria Esposito, Carlo Famoso, Arturo Buscarino   +3 more
wiley   +1 more source

A PMOS tunneling photodetector [PDF]

IEEE Transactions on Electron Devices, 2001
A metal/oxide/n-Si structure with ultrathin gate oxide is utilized as a photodetector. At inversion gate bias, the dark current and photocurrent are determined by both the minority carrier (hole) generation rate in the deep depletion region and the electrons tunneling from the gate electrode to n-type Si, while only the former component is significant ...
Hsu, B.-C., Liu, C.W., Liu, W.T., Lin, C.-H.   +3 more
openaire   +1 more source

The Influence of Residual Ion Drift During Programming of Chip‐Integrated Nanoscale HfO2‐Based Memristive Devices

Advanced Electronic Materials, EarlyView.
1T1R‐arrays combining filamentary‐type memristors and CMOS transistors offer great potential for energy‐efficient analog hardware accelerators. Here, transient SET analysis of nanoscale HfO2 memristors integrated on 180 nm CMOS wafers is discussed.
Oliver Artner, Felix Cüppers, Seokki Son, Yang Chen, Xiaohua Liu, Christopher Bengel, Dennis Nielinger, André Zambanini, Stefan Wiefels, Stephan Menzel, Regina Dittmann, Susanne Hoffmann‐Eifert   +11 more
wiley   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source