Results 41 to 50 of about 41,654 (227)

HUBUNGAN KEBERADAAN PENGAWAS MENELAN OBAT DENGAN KEPATUHAN MINUM OBAT PASIEN TUBERKULOSIS DI PUSKESMAS CIMAHI SELATAN KOTA CIMAHI

open access: yesJurnal Kesehatan Budi Luhur, 2023
Pada tahun 2020, 9,9 juta telah didiagnosis dengan tuberkulosis (TB) dan 1,5 juta tidak mendapat pengobatan TB Salah satu dari delapan negara yang memiliki kasus TB ke dua terbanyak di dunia adalah Indonesia.
Dwi Yulnovianti   +2 more
doaj   +1 more source

Dielectric and Gate Metal Engineering for Threshold Voltage Modulation in Enhancement Mode Monolayer MoS2 Field Effect Transistors

open access: yesAdvanced Materials, EarlyView.
Enhancement‐mode monolayer MoS2 FETs with low threshold voltage are essential for low‐power electronics. The threshold voltage can be tuned by the gate metal work function when the semiconductor/dielectric interface is clean. Interfaces between monolayer MoS2 and ZrO2 or hBN allow effective work‐function modulation of the threshold voltage, in contrast
Lixin Liu   +10 more
wiley   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

open access: yesAdvanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin   +6 more
wiley   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

open access: yesAdvanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng   +15 more
wiley   +1 more source

WGCNA Identification of Genes and Pathways Involved in the Pathogenesis of Postmenopausal Osteoporosis

open access: yesInternational Journal of General Medicine, 2021
Meng-Lei Hao,1,* Xiao-Qin Zuo,2,* Yong Qiu,3,* Jian Li1 1Department of Endocrinology, Zigong First People’s Hospital, Zigong Academy of Medical Sciences, Zigong, Sichuan Province, People’s Republic of China; 2Department of Geriatric Medicine,
Hao ML, Zuo XQ, Qiu Y, Li J
doaj  

Peptide Receptor‐Functionalized AuNP‐Embedded Zwitterionic Biopolymeric Nanohydrogel for Electrochemical Sclerostin Sensing

open access: yesAdvanced Science, EarlyView.
We report an electrochemical biosensor that employs biopanning‐derived affinity peptides as selective receptors on a multifunctional chitosan–zwitterionic–gold nanoparticle (CS–ZI–AuNPs) nanohydrogel interface. The CS–ZI–AuNPs nanohydrogel exhibits antifouling properties, abundant sites for stable peptide immobilization, and efficient electrochemical ...
Hyo Jeong Yang   +6 more
wiley   +1 more source

ReRAM/CMOS Array Integration and Characterization via Design of Experiments

open access: yesAdvanced Electronic Materials, EarlyView.
This paper proposes the Design of Experiments to characterize arrays of oxide‐based ReRAM devices by exploring the large characterization space efficiently using only a few numbers of experiments. Using in‐house integration of 20 000 ReRAM devices on a CMOS chip, the unconventional optimization approach determines optimized measurement parameters and ...
Imtiaz Hossen   +7 more
wiley   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

open access: yesAdvanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

Self-transfecting GMO-PMO chimera targeting Nanog enable gene silencing in vitro and suppresses tumor growth in 4T1 allografts in mouse

open access: yesMolecular Therapy: Nucleic Acids, 2023
Phosphorodiamidate morpholino oligonucleotide (PMO)-based antisense reagents cannot enter cells without the help of a delivery technique, which limits their clinical applications. To overcome this problem, self-transfecting guanidinium-linked morpholino (
Ujjal Das   +8 more
doaj   +1 more source

Al-Mg systematics of hibonite-bearing Ca,Al-rich inclusions from Ningqiang [PDF]

open access: yes, 2011
Hibonite-bearing Ca,Al-rich inclusions (CAIs) usually occur in CM and CH chondrites and possess petrographic and isotopic characteristics distinctive from other typical CAIs.
Guan, Yunbin, Hsu, Weibiao, Wang, Ying
core  

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