Frontiers in Endocrinology, 2022 ObjectivesLymph node metastases (LNMs) could be stratified into clinical N1 (cN1) and microscopic pN1 (pathological N1), which bear different biological behavior and prognosis.
Qiuyang Li
exaly +4 more sources
Industrial Crops and ProductsPanax notoginseng, a valuable plant used in traditional Chinese medicine, is often difficult to cultivate because of its susceptibility to various diseases, including root rot.
Gan Kunfa +5 more
exaly +4 more sources
Prognostic Stratification of pN1 Prostate Cancer After Radical Prostatectomy: A Competing Risk Analysis from a Multi-institutional Cohort [PDF]
European Urology Open ScienceBackground and objective: Lymph node–positive (pN1) prostate cancer (PCa) is a heterogeneous disease, and a clear definition of prognostic groups is urgently needed.
Lorenzo Tosco +2 more
exaly +4 more sources
Scientific Reports, 2023 The aim of our study was to determine the clinical utility of neutrophil-to-lymphocyte ratio (NLR) in predicting presence and prognosis of nodal involvement in patients treated with radical prostatectomy (RP) due to prostate cancer.
Piotr Zapała +10 more
doaj +2 more sources
The role of postoperative radiotherapy in pN1 oral cavity cancer without extranodal extension
World Journal of Surgical Oncology, 2021 Background The administration of postoperative radiotherapy remains controversial in pN1 oral cavity cancer patients without extranodal extension. The aim is to determine whether postoperative radiotherapy reduces the neck recurrence rate and improves ...
Tsung-You Tsai +6 more
doaj +2 more sources
Cancers, 2023 Simple Summary In brief, this is the first prospective study using a multicentric approach to investigate the effectiveness of adjuvant radiotherapy in patients with early squamous cell carcinoma of the oral cavity (T1/2) and the oropharynx (T1) with one
Peer Wolfgang Kämmerer +2 more
exaly +2 more sources
Postoperative radiotherapy to the neck for pN1 status HNSCC patients after neck dissection
Scientific Reports, 2022 The significance of postoperative radiotherapy (PORT) to the neck for pN1 status head and neck squamous cell carcinomas (HNSCC) after neck dissection is unclear.
Jia Wang +10 more
doaj +2 more sources
Identification of a Binding Site in Protease Nexin I (PN1) Required for the Receptor Mediated Internalization of PN1-Thrombin Complexes [PDF]
Journal of Biological Chemistry, 1997 An overlapping synthetic peptide library was constructed representing most of the mature protease nexin I (PN1) sequence from the amino terminus to the reactive center. This library, along with peptides from the heparin binding domain and from the region carboxyl-terminal to the P1 residue of the cleavage site, was screened for the inhibition of 125I ...
M F, Knauer, S B, Hawley, D J, Knauer
exaly +3 more sources
External Validation of Nomograms for Predicting Pelvic Lymph Node Metastases in Patients with Prostate Cancer and the Added Value of the Prostate-specific Membrane Antigen Positron Emission Tomography–based PRIMARY Score [PDF]
European Urology Open ScienceBackground and objective: The aim of our study was to predict pathological lymph node involvement (stage pN1) in patients undergoing radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND) for prostate cancer (PC) and to compare the ...
Muhammet Demirbilek +7 more
doaj +2 more sources
Postoperative radiotherapy versus surgery alone in pN1 oral cavity cancer patients: A meta‐analysis
Laryngoscope Investigative OtolaryngologyObjectives The aim of this meta‐analysis is to evaluate the potential benefits of postoperative radiotherapy (PORT) in patients with pN1 oral cavity squamous cell carcinoma.
Tsung‐You Tsai +10 more
doaj +2 more sources