Frontiers in Endocrinology, 2022 ObjectivesLymph node metastases (LNMs) could be stratified into clinical N1 (cN1) and microscopic pN1 (pathological N1), which bear different biological behavior and prognosis.
Qiuyang Li, Yukun Luo, Ren Ling
exaly +3 more sources
Identification of a Binding Site in Protease Nexin I (PN1) Required for the Receptor Mediated Internalization of PN1-Thrombin Complexes [PDF]
Journal of Biological Chemistry, 1997 An overlapping synthetic peptide library was constructed representing most of the mature protease nexin I (PN1) sequence from the amino terminus to the reactive center. This library, along with peptides from the heparin binding domain and from the region carboxyl-terminal to the P1 residue of the cleavage site, was screened for the inhibition of 125I ...
Mary F Knauer, Daniel J Knauer
exaly +3 more sources
External Validation of Nomograms for Predicting Pelvic Lymph Node Metastases in Patients with Prostate Cancer and the Added Value of the Prostate-specific Membrane Antigen Positron Emission Tomography–based PRIMARY Score [PDF]
European Urology Open ScienceBackground and objective: The aim of our study was to predict pathological lymph node involvement (stage pN1) in patients undergoing radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND) for prostate cancer (PC) and to compare the ...
Muhammet Demirbilek +7 more
doaj +2 more sources
Peer review of the pesticide risk assessment of the active substance Pasteuria nishizawae Pn1
EFSA Journal, 2018 The conclusions of EFSA following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, Denmark, for the pesticide active substance Pasteuria nishizawae Pn1 are reported. The context of the
Stefania Barmaz +2 more
exaly +2 more sources
Industrial Crops and ProductsPanax notoginseng, a valuable plant used in traditional Chinese medicine, is often difficult to cultivate because of its susceptibility to various diseases, including root rot.
Liu Diqiu
exaly +3 more sources
Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model [PDF]
Frontiers in ImmunologyChildhood vaccination provides protection against infectious diseases, but multiple vaccinations are required to achieve this. In situations like influenza epidemics or COVID-19 pandemic, vaccine demands may exceed production capacity, highlighting the ...
Jenny Lorena Molina Estupiñan +14 more
doaj +2 more sources
Postmastectomy radiotherapy in pN1 breast cancer: Survival outcomes and prognostic factors from a single-institution cohort. [PDF]
PLoS ONEPurpose/objectivesThe role of postmastectomy radiotherapy (PMRT) in patients with pathologic N1 (pN1) breast cancer, including triple-negative breast cancer (TNBC), remains controversial in the era of modern systemic therapy. We evaluated the association
Raksha M Narasimhan +7 more
doaj +2 more sources
Anatomical distribution of disease in pN1 prostate cancer with BCR post‐RP: A PSMA‐PET/CT‐based analysis [PDF]
BJUI CompassObjectives To explore the distribution of metastatic disease in pN1 patients with biochemical recurrence (BCR) assessed by Prostate‐Specific Membrane Antigen‐Positron‐Emission/Computed Tomography (PSMA‐PET/CT).
Lotte G. Zuur +11 more
doaj +2 more sources
Correlation between clinical and pathological nodal status in hepatocellular carcinoma: identifying risk factors for lymph node metastasis via the national cancer database [PDF]
World Journal of Surgical OncologyBackground Lymph node metastasis (LNM) in hepatocellular carcinoma (HCC) is associated with significantly worse prognosis, yet its detection and risk stratification remain challenging in clinical practice.
Huisong Lee +5 more
doaj +2 more sources
European Urology Open ScienceBackground and objective: Lymph node–positive (pN1) prostate cancer (PCa) is a heterogeneous disease, and a clear definition of prognostic groups is urgently needed.
Giansilvio Marchioro +1 more
exaly +3 more sources