Results 101 to 110 of about 51,393 (251)

Recent Advances in Chemical Modification of Peptide Nucleic Acids

open access: yesJournal of Nucleic Acids, 2012
Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology. Although PNA recognizes single-stranded nucleic acids with exceptionally high affinity and sequence selectivity, there is considerable ongoing effort to further ...
Eriks Rozners
doaj   +1 more source

PNA-Functionalized, Silica Nanowires-Filled Glass Microtube for Ultrasensitive and Label-Free Detection of miRNA-21

open access: yes
MicroRNAs (miRNAs) are endogenous and noncoding single-stranded RNA molecules with a length of approximately 18–25 nucleotides, which play an undeniable role in early cancer screening.
Yisha Jiang (17896175)   +8 more
core   +1 more source

Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong   +4 more
wiley   +1 more source

Extended DNA-Recognition Repertoire of Peptide Nucleic Acid (PNA): PNA-dsDNA triplex formed with cytosine-rich homopyrimidine PNA

open access: yes, 1997
Peptide nucleic acid (PNA) is an oligonucleotide mimic in which the backbone of DNA has been replaced by a pseudopeptide. Thymine-rich homopyrimidine PNA oligomers have been found to recognize double-stranded DNA targets by displacement of the pyrimidine
Nordén, Bengt,   +5 more
core   +1 more source

The first synthesis of chiral PNA monomer-cyclen conjugates [PDF]

open access: yes, 2005
A synthetic route to novel chiral PNA monomer-cyclen conjugates was described for the first time, the targeted products were obtained in high yields under mild reaction conditions.
You, JS   +7 more
core  

Artificial structures for human‐machine interfaces with closed‐loop interaction

open access: yesFlexMat, EarlyView.
Artificial structures bridge sensing and feedback in closed‐loop human‐machine interfaces by providing geometry‐enabled mechanical and functional programmability. This review maps the role of artificial structures in diverse sensing modalities and feedback strategies, and illustrates their integration into closed‐loop interaction systems, highlighting ...
Taiqi Hu   +4 more
wiley   +1 more source

From Isolation to Integration: Harnessing Restorative Clinical Supervision Within the A‐EQUIP Model to Support Internationally Educated Radiographers in the UK

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Internationally educated radiographers face isolation, unfamiliar hierarchies and discrimination risk when transitioning to UK practice. Embedding restorative clinical supervision within the A‐EQUIP model offers a practical, evidence‐informed framework to reduce isolation and improve retention within radiography departments. AI statement: The graphical
Dorothy Cox, Andrea Stebbings
wiley   +1 more source

Intracellular Localization of PNA in Human Cells upon its Introduction by Electroporation

open access: yesNatural Product Communications, 2012
Peptide nucleic acid (PNA) is one of the most useful DNA analogs in a wide variety of gene analysis in human cells. In order to exhibit its maximal functions, PNA must be localized to a desired place (e.g., nucleus, cytoplasm and other organelles). Here,
Eri Noguchi   +2 more
doaj   +1 more source

Frequent, Intense and Prolonged Human‐Perceived Heat Waves Over the Arabian Peninsula in Recent Decades

open access: yesInternational Journal of Climatology, EarlyView.
The spatial distribution of WBGT exhibits a widespread and significant warming trend across the Arabian Peninsula (AP), with, particularly, strong increases observed over the central and northern inland and eastern coastal regions of Saudi Arabia, Kuwait and Qatar, where trends exceed ~0.25°C decade−1.
Safi Ullah   +7 more
wiley   +1 more source

Differences in the Evaluation and Diagnosis of Obstructive Sleep Apnea by Sex: A Systematic Review

open access: yesThe Laryngoscope, EarlyView.
This systematic review of 33 studies found that females with obstructive sleep apnea generally presented at an older age and with higher BMI, whereas males generally had greater neck circumference and apnea‐hypopnea index. These findings highlight clinically relevant sex‐based differences in OSA evaluation and support more individualized approaches to ...
Alexandra Vacaru   +6 more
wiley   +1 more source

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