Results 221 to 230 of about 133,257 (324)

Serotonergic Neuromodulation of Natural Products Isoreserpine and Isoreserpiline in Adult Zebrafish: An in Silico and In Vivo Investigation

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Anxiety is a multidimensional behavioral disorder widely studied in neuroscience due to the involvement of specific neural circuits. Although benzodiazepines are commonly used, their side effects drive the search for new therapeutic alternatives.
Nádia Aguiar Portela Pinheiro, Ivana Carneiro Romão, Amanda Maria Barros Alves, Sônia Maria Costa Siqueira, Jane Eire Silva Alencar de Menezes, Emmanuel Silva Marinho, Maria Kueirislene Amâncio Ferreira, Márcia Machado Marinho, Herbert de Sousa Magalhães, Andreia Ferreira de Castro Gomes, Otília Deusdênia Loiola Pessoa, Hélcio Silva dos Santos   +11 more
wiley   +1 more source

Evaluation of Peptide Nucleic Acid Encapsulation in Ferritin Nanocages for Gene Silencing Applications. [PDF]

Biomacromolecules
Falanga AP, Farina MV, Cianfoni G, Barolo L, Di Meo C, Borsatti GE, Ghirga F, Botta B, Pisano L, Borbone N, D'Errico S, Paone A, Oliviero G, Quaglio D, Baiocco P.   +14 more
europepmc   +1 more source

PNAs methodology

Personal network analysis.
openaire   +1 more source

NLK facilitates Caspase‐8 activation to drive macrophage PANoptosis in sepsis

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
By promoting Caspase‐8 activation within the PANoptosome, NLK modulates pyroptotic, apoptotic, and necroptotic programs in macrophages, thereby driving inflammatory injury and multiorgan damage during sepsis. Abstract Mounting evidence indicates that macrophage PANoptosis—an integrated inflammatory cell‐death program comprising pyroptosis, apoptosis ...
Yun Xia, Ren‐qi Yao, Hui‐fan Liu, Guo‐qing Jing, Delida Aidebaike, Jing Zuo, Shi‐qi Wan, Die Wu, Peng‐yue Zhao, Hai‐long Gong, Xing Wang, Hui‐min Zhou, Ning Dong, Yao Wu, Shi Liu, Xiao‐jing Wu, Yong‐ming Yao, Xue‐min Song   +17 more
wiley   +1 more source

Phase transition driven tough hydrogel ionic thermoelectric cell with giant thermopower. [PDF]

Nat Commun
Shi X, Li Y, Shi N, Ji C, Hou L, Shi Y, Xu J, Lan Y, Wei Q, Ma G, Wu P, Hu Z.   +11 more
europepmc   +1 more source

Jaguar Density at the Northeastern Limit of Its Distribution in Mexico

Ecology and Evolution, Volume 16, Issue 2, February 2026.
This study presents the first estimate of jaguar density in northeastern Mexico using a spatial capture–recapture model with random thinning, which incorporates both identified and unidentified camera trap detections. Conducted over 91 days with 104 cameras, the model yielded a density of 1.29 individuals per 100 km2 in the El Cielo–Sierra de Tamalave ...
Zavdiel A. Manuel‐de la Rosa, Leroy Soria‐Díaz, Carlos Barriga‐Vallejo, Gabriela R. Mendoza‐Gutiérrez, Nayeli Martínez‐González, Claudia C. Astudillo‐Sánchez, José Jiménez   +6 more
wiley   +1 more source

Developing antisense oligomer biotics "asobiotics" as precision antibacterials: designs, strategies, and considerations for future success. [PDF]

FEMS Microbiol Rev
Moustafa DA, Ghosh C, Jung J, Nanayakkara A, Sapkota M, Nagamatsu K, Geller B, Vogel J, Goldberg JB, Greenberg DE.   +9 more
europepmc   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Renal maturation and catch-up clearance of ganciclovir in a preterm neonate: Bayesian pharmacokinetic analysis using a population model. [PDF]

J Pharm Health Care Sci
Kata K, Inomata S, Nishikawa M, Ide H, Nakamura K, Yoshida T, Taguchi M.   +6 more
europepmc   +1 more source

The Relationship Between Immunopathology and Body Condition of Mixed‐Age Ewes

New Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
Ill thrift in ewes, characterised by less than desirable body condition, is a multifactorial condition often attributed to nutritional deficits, though immunopathological factors may also play a role. This study investigated associations between body condition scores (BCS) and immunopathological states in 120 mixed‐age ewes grazing pasture over 4 ...
Melissa N. Hempstead, Sandeep K. Gupta, Paul M. Candy, Rina Hannaford, Dave M. Leathwick, Chris M. Miller, Anne L. Ridler, Mallory A. Ross, Laura B. Hunter, Trevor J. Watson, Tania A. Wilson, Karin E. Schütz, Alex K. Chambers, Christian W. Sauermann, Cheryl E. O’Connor, Natalie A. Parlane   +15 more
wiley   +1 more source