Results 51 to 60 of about 33,360 (259)
Molecular Therapy: Nucleic Acids, 2017 Peptide nucleic acids (PNAs) are potentially attractive antisense agents against hepatitis B virus (HBV), although poor cellular uptake limits their therapeutic application.
Bénédicte Ndeboko +5 more
doaj +1 more source
Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges
Advanced Materials Technologies, EarlyView.This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.This review presents recent progress in vision‐augmented wearable interfaces that combine artificial vision, soft wearable sensors, and exoskeletal robots. Inspired by biological visual systems, these technologies enable multimodal perception and intelligent human–machine interaction.
Jihun Lee +4 more
wiley +1 more source
A Template‐Mediated Click–Click Reaction: PNA–DNA, PNA–PNA (or Peptide) Ligation, and Single Nucleotide Discrimination [PDF]
European Journal of Organic Chemistry, 2010 AbstractA highly efficient chemical ligation was developed for quantitative conjugation of PNA with DNA (PNA or peptide) by using the copper‐catalyzed azide–alkyne cycloaddition reaction. Whereas PNAs with an alkyne at the C‐terminus and an azide at the N‐terminus have been used, an efficient click–click reaction occurs.
Xiaohua, Peng +2 more
openaire +2 more sources
Advanced Robotics Research, EarlyView.This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska +2 more
wiley +1 more source
Advanced Robotics Research, EarlyView.Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source
Advances in Electroactive Liquid Crystal Elastomers for Intelligent Robotics and Electronics
Advanced Robotics Research, EarlyView.Electroactive liquid crystal elastomers (eLCEs) integrate molecular anisotropy with electrical functionality to enable programmable actuation and reconfigurable electronics. This review classifies eLCEs into robotic actuators and adaptive electronics, summarizes key actuation mechanisms, and highlights fabrication strategies that bridge materials to ...
Kavita Ramesh Rathod +14 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2015 Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been
Camilla Brolin +5 more
doaj +1 more source
A new concept in double duplex DNA invasion by chiral PNAs which simultaneously depress PNA-PNA and improve PNA-DNA duplex stability. [PDF]
Nucleic Acids Symposium Series, 2007 By using suitably designed chiral, lysine-based PNAs (chPNAs), the stability of complementary chPNAchPNA duplexes can be depressed, maintaining or improving at the same time the stability of the corresponding PNA-DNA duplexes. This approach could be used in order to develop chPNAs able to perform double duplex DNA invasion.
SFORZA, Stefano +3 more
openaire +3 more sources
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source