Results 61 to 70 of about 33,360 (259)
Automated Detection of Point Mutations by Electrophoresis in Peptide-Nucleic Acid-Containing Gels
BioTechniques, 1999 Polymerization of electronically, essentially neutral peptide nucleic acids (PNA) into polyacrylamide gels creates a medium in which the salt-independent properties of PNA/DNA interactions are used to achieve hybridization with target DNA during affinity
Gabor L. Igloi
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Machine Learning Guides Peptide Nucleic Acid Flow Synthesis and Sequence Design
Advanced Science, 2022 Peptide nucleic acids (PNAs) are potential antisense therapies for genetic, acquired, and viral diseases. Efficiently selecting candidate PNA sequences for synthesis and evaluation from a genome containing hundreds to thousands of options can be ...
Chengxi Li +6 more
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Strand invasion by mixed base PNAs and a PNA-peptide chimera [PDF]
Nucleic Acids Research, 2000 Peptide nucleic acid oligomers (PNAs) have a remarkable ability to invade duplex DNA at polypurine-polypyrimidine target sequences. Applications for PNAs in medicine and biotechnology would increase if the rules governing their hybridization to mixed base sequences were also clear.
X, Zhang, T, Ishihara, D R, Corey
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Advanced Science, EarlyView.ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu +12 more
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Progress in Strain Engineering of 2D‐Integrated Heterostructures for Ultrasensitive Sensors
Advanced Science, EarlyView.. ABSTRACT Two‐dimensional (2D) integrated heterostructures have emerged as a cornerstone in the advancement of next‐generation sensor technologies. These heterostructures, which combine materials with different dimensionalities, have led to significant breakthroughs in sensing performance and device integration.
That Buu Ton +4 more
wiley +1 more source
Estradiol resolves pneumonia via ERβ in regulatory T cells
JCI Insight, 2021 Current treatments for pneumonia (PNA) are focused on the pathogens. Mortality from PNA-induced acute lung injury (PNA-ALI) remains high, underscoring the need for additional therapeutic targets.
Ye Xiong +7 more
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Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
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Proceedings of the National Academy of Sciences, 2003 The Proceedings will … serve as a medium for the prompt publication of brief original papers by members of the Academy and other American investigators. Its aim will be to furnish a comprehensive survey of the more important results of … scientific research . . . . .
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Advanced Electronic Materials, EarlyView.This paper reviews the physics of liquid metals in RF devices, including the influence of mechanical strain on resonance as well as fabrication methods and strategies for designing tunable and strain‐tolerant inductors, capacitors, and antennas.
Md Saifur Rahman, William J. Scheideler
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Topological Materials and Related Applications
Advanced Electronic Materials, EarlyView.This review covers topological materials—including topological insulators, quantum valley Hall and quantum spin Hall insulators, and topological Weyl and Dirac semimetals—as well as their most recent advancements in fields such as spintronics, electronics, photonics, thermoelectrics, and catalysis.
Carlo Grazianetti +9 more
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