Results 71 to 80 of about 51,393 (251)
PNA-FISH assay optimisation flowchart using pure bacterial culture.
, 2019 Four optimisation protocols were performed one of each for formamide concentration, hybridization temperature, probe concentration, and hybridization duration.
Xiao Xuan Huang (6316268) +2 more
core +1 more source
Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution
Advanced Science, EarlyView.MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge +6 more
wiley +1 more source
Advanced Science, EarlyView.Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley +1 more source
Electrically Tuning Electromagnetic Wave Shielding in Phase Engineered 1T/2H‐MoS2‐Based Devices
Advanced Electronic Materials, EarlyView.Sub‐millimeter‐thick phase‐engineered 1T/2H‐MoS2 structures enable electrically tunable electromagnetic interference shielding through active modulation of microwave absorption and reflection. The coexistence of metallic and semiconducting phases, combined with a PVA/KOH gel electrolyte, provides dynamic control over charge transport and interfacial ...
Mustafa Akyol +3 more
wiley +1 more source
Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells
Advanced Energy Materials, EarlyView.Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu +4 more
wiley +1 more source
Estradiol resolves pneumonia via ERβ in regulatory T cells
JCI Insight, 2021 Current treatments for pneumonia (PNA) are focused on the pathogens. Mortality from PNA-induced acute lung injury (PNA-ALI) remains high, underscoring the need for additional therapeutic targets.
Ye Xiong +7 more
doaj +1 more source
Heterotriplex-forming PNA in the targeting of the Bcl-2 P1 promoter in anticancer treatment
, 2021 Among several anti-gene strategies, the use of DNA analogues such as Peptide Nucleic Acids (PNAs) represents a promising tool for the modulation of gene transcription thanks to their chemical and enzymatic stability and the absence of charges in their ...
Stefano D'Errico +7 more
core
Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries
Advanced Energy Materials, EarlyView.This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu +5 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2015 Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been
Camilla Brolin +5 more
doaj +1 more source
Automated Detection of Point Mutations by Electrophoresis in Peptide-Nucleic Acid-Containing Gels
BioTechniques, 1999 Polymerization of electronically, essentially neutral peptide nucleic acids (PNA) into polyacrylamide gels creates a medium in which the salt-independent properties of PNA/DNA interactions are used to achieve hybridization with target DNA during affinity
Gabor L. Igloi
doaj +1 more source