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Genetic diversity of Streptococcus pneumoniae causing meningitis and sepsis in Singapore during the first year of PCV7 implementation [PDF]

open access: yesEmerging Microbes and Infections, 2014
Streptococcus pneumoniae is a major cause of sepsis, meningitis and respiratory disease worldwide. Pneumococcal conjugate vaccines (PCVs) have now been implemented in many countries worldwide, including Singapore.
Elita Jauneikaite   +5 more
doaj   +4 more sources

Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]

open access: diamondKorean Journal of Pediatrics, 2014
The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
doaj   +3 more sources

Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping. [PDF]

open access: yes, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Adhikari, N   +12 more
core   +25 more sources

Effect of pneumococcal conjugate vaccine six years post-introduction on pneumococcal carriage in Ulaanbaatar, Mongolia [PDF]

open access: yesNature Communications
Limited data from Asia are available on long-term effects of pneumococcal conjugate vaccine introduction on pneumococcal carriage. Here we assess the impact of 13-valent pneumococcal conjugate vaccine (PCV13) introduction on nasopharyngeal pneumococcal ...
Claire von Mollendorf   +19 more
doaj   +2 more sources

Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine.

open access: yesPLoS ONE, 2022
Pneumococcal conjugate vaccines reduce the burden of invasive pneumococcal disease, but the sustained effect of these vaccines can be diminished by an increase in disease caused by non-vaccine serotypes.
Sweta M Patel   +15 more
doaj   +3 more sources

Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia. [PDF]

open access: yesPLoS Medicine, 2005
Pneumonia remains the leading cause of death in young children. The poor specificity of chest radiographs (CXRs) to diagnose pneumococcal pneumonia may underestimate the efficacy of pneumococcal conjugate vaccine in preventing pneumococcal pneumonia.The ...
Shabir A Madhi   +3 more
doaj   +1 more source

Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea [PDF]

open access: yesKorean Journal of Pediatrics, 2011
Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults.
Eun Hwa Choi   +9 more
doaj   +1 more source

Pneumococcal Conjugate Vaccination Followed by Pneumococcal Polysaccharide Vaccination in Lung Transplant Candidates and Recipients

open access: yesTransplantation Direct, 2020
Background. Pneumococcal conjugate vaccination as well as pneumococcal polysaccharide vaccination are recommended for lung transplant candidates and recipients, but the combination of these vaccines has not been extensively studied in these specific ...
Thijs W. Hoffman, MD   +4 more
doaj   +1 more source

A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]

open access: yes, 2010
BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.
French, N   +9 more
core   +4 more sources

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