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Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis [PDF]

open access: yesNew England Journal of Medicine, 2009
Invasive pneumococcal disease declined among children and adults after the introduction of the pediatric heptavalent pneumococcal conjugate vaccine (PCV7) in 2000, but its effect on pneumococcal meningitis is unclear.We examined trends in pneumococcal meningitis from 1998 through 2005 using active, population-based surveillance data from eight sites in
Matthew R. Moore   +15 more
openaire   +3 more sources

A Phase II Trial of Safety, Tolerability and Immunogenicity of V114, a 15-Valent Pneumococcal Conjugate Vaccine, Compared With 13-Valent Pneumococcal Conjugate Vaccine in Healthy Infants

open access: yesThe Pediatric Infectious Disease Journal, 2020
Supplemental Digital Content is available in the text. Background: Pneumococcal disease remains a public health priority worldwide. This phase 2 study (V114-008; NCT02987972; EudraCT 2016-001117-25) compared safety and immunogenicity of 2 clinical lots ...
H. Platt   +14 more
semanticscholar   +1 more source

Effectiveness of pneumococcal conjugate vaccines against invasive pneumococcal disease among children under five years of age in Africa: A systematic review.

open access: yesPLoS ONE, 2019
BackgroundDespite the widespread implementation of the pneumococcal conjugate vaccine, Streptococcus pneumoniae remains the leading cause of severe pneumonia associated with mortality among children less than 5 years of age worldwide, with the highest ...
James Samwel Ngocho   +6 more
doaj   +1 more source

Use of 13-Valent Pneumococcal Conjugate Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine Among Adults Aged ≥65 Years: Updated Recommendations of the Advisory Committee on Immunization Practices

open access: yesMMWR. Morbidity and mortality weekly report, 2019
Two pneumococcal vaccines are currently licensed for use in adults in the United States: a 13-valent pneumococcal conjugate vaccine (PCV13 [Prevnar 13, Pfizer, Inc.]) and a 23-valent pneumococcal polysaccharide vaccine (PPSV23 [Pneumovax 23, Merck and Co.
Almea M Matanock   +5 more
semanticscholar   +1 more source

Impact and effectiveness of 13-valent pneumococcal conjugate vaccine on population incidence of vaccine and non-vaccine serotype invasive pneumococcal disease in Blantyre, Malawi, 2006–18: prospective observational time-series and case-control studies

open access: yesLancet Global Health, 2020
Summary Background The population impact of pneumococcal conjugate vaccines (PCVs) depends on direct and indirect protection. Following Malawi's introduction of the 13-valent PCV (PCV13) in 2011, we examined its impact on vaccine and non-vaccine serotype
N. Bar-Zeev   +16 more
semanticscholar   +1 more source

Invasive Pneumococcal Disease 3 Years after Introduction of 10-Valent Pneumococcal Conjugate Vaccine, the Netherlands

open access: yesEmerging Infectious Diseases, 2015
Three years after a 7-valent pneumococcal conjugate vaccine was replaced by a 10-valent pneumococcal conjugate vaccine in the Netherlands, we observed a decrease in incidence of invasive pneumococcal disease caused by Streptococcus pneumoniae serotypes 1,
Mirjam J. Knol   +6 more
doaj   +1 more source

Invasive pneumococcal infection due to serotype 15A after the pneumococcal conjugate vaccine implementation in Turkey

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Invasive pneumococcal infections among children are a serious public health problem in many countries, including Turkey. Pneumococcal conjugate vaccine has been included in Turkey's National Immunization Programme since 2009.
Ayşe Büyükcam   +6 more
doaj   +1 more source

Pneumococcal Conjugate Vaccine Breakthrough Infections: 2001–2016

open access: yesPediatrics, 2020
Using population-based national surveillance data, we compared rates of IPD among children
T. Adebanjo   +18 more
semanticscholar   +1 more source

Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults.

open access: yesNew England Journal of Medicine, 2015
BACKGROUND Pneumococcal polysaccharide conjugate vaccines prevent pneumococcal disease in infants, but their efficacy against pneumococcal community-acquired pneumonia in adults 65 years of age or older is unknown. METHODS In a randomized, double-blind,
M. Bonten   +27 more
semanticscholar   +1 more source

Adesão às novas vacinas conjugadas. Vacina anti-meningocócica e anti-pneumocócica.

open access: yesActa Médica Portuguesa, 2004
The new conjugate vaccines against group C meningococcal infection and pneumococcal infection were introduced in Portugal in 2001. In 2001/2002, the media published several alarming news on meningococcal disease and there was an increased demand of those
Laurinda De Queirós   +3 more
doaj   +1 more source

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