Results 61 to 70 of about 36,270 (220)

Invasive pneumococcal disease in relation to vaccine type serotypes

Human Vaccines & Immunotherapeutics, 2019
Since 1983 the world has been introduced to four vaccines combating disease caused by Streptococcus pneumoniae bacteria. However, despite vaccination programs disease caused by S.
Paeton L. Wantuch, Fikri Y. Avci
doaj   +1 more source

Lessons learnt after the introduction of the seven valent-pneumococcal conjugate vaccine toward broader spectrum conjugate vaccines

Biomedical Journal, 2012
The 7-valent pneumococcal conjugate vaccine (PCV7) is currently being introduced in the vaccine schedule of over 90 countries around the world. After the introduction of the PCV7 vaccine in the United States, a reduction of more than 90% of invasive ...
Oana Falup-Pecurariu
doaj   +1 more source

Immunological efficacy of pneumococcal vaccine strategies in HIV-infected adults: a randomized clinical trial [PDF]

, 2016
The aim of this study was to compare the immunologic response to a prime-boost immunization strategy combining the 13-valent conjugate pneumococcal vaccine (PCV13) with the 23-valent polysaccharide pneumococcal vaccine (PPSV23) versus the PPSV23 alone in
Bennett, Kathleen, Bergin, C, Conlon, N, Dunne, J, O\u27Dea, S, Sadlier, C   +5 more
core   +1 more source

‘I Think From the Beginning, the Ambitions Were Compromised’: A Case Study of COVAX as Vaccine Equity Policy Operationalisation

The International Journal of Health Planning and Management, Volume 41, Issue 1, Page 59-70, January 2026.
ABSTRACT Background COVAX was designed to support the discovery, development, and distribution of COVID‐19 vaccines globally, at scale and pace. This article examines how COVAX promoted vaccine equity and what lessons can be learnt. Methods Informed by a scoping review of lessons learnt from GHPs, we reviewed 109 documents related to COVAX and other ...
Charnele Nunes, Martin Mckee, Simon Rushton, Natasha Howard   +3 more
wiley   +1 more source

Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage, United States, 2015–2016

Emerging Infectious Diseases, 2017
We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United States during 2015–2016 and related these findings to previous serotype 35B IPD data obtained ...
Sopio Chochua, Benjamin J. Metcalf, Zhongya Li, Hollis Walker, Theresa Tran, Lesley McGee, Bernard Beall   +6 more
doaj   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

Protein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee, Jasmina S. Redzic, Blaine Gordon, Anthony J. Saviola, Norman Tran, Sean P. Maroney, Nathanael L. Ashby, Steven Shaw, Sam Fulte, Arianna McCarty, Todd Holyoak, Nancy Meyer, Kirk C. Hansen, Sarah E. Clark, Elan Eisenmesser   +14 more
wiley   +1 more source

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000–2019: protocol for systematic review

BMJ Open, 2019
Introduction Africa harbours a high burden of pneumococcal disease, with associated high mortality rates. Despite 34 countries introducing the pneumococcal conjugate vaccine, which reduces the risk of pneumococcal carriage (a prerequisite for disease) of
Neil French, Dean Everett, Newton L. Kalata, Tinashe K. Nyazika, Todd D. Swarthout, Robert S. Heyderman, Stephen B. Gordon, Kondwani C. Jambo   +7 more
doaj   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Clagnan, E, Cocchio, Silvia, Del Zotto, S, Furlan, Patrizia, Gallo, T, Saia, Mario   +9 more
core   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Serotypes in Adult Pneumococcal Pneumonia in Spain in the Era of Conjugate Vaccines [PDF]

, 2021
Lucía Fernández-Delgado, Jordi Cámara, Aída González-Díaz, Inmaculada Grau, Hisashi Shoji, Fé Tubau, Sara Martí, M.Á. Domínguez, Jordi Carratalà, José Yuste, Carmen Ardanuy   +10 more
openalex   +1 more source