Results 51 to 60 of about 1,128 (134)
The article presents the review aimed at summarizing the opinions on the epidemiology of pneumococcal infection and the most effective measures for its prevention.
Leyla S. Namazova-Baranova +4 more
doaj +1 more source
Complement‐Dominant Relapse of Mixed Autoimmune Hemolytic Anemia After Rituximab Response
ABSTRACT Introduction Mixed autoimmune hemolytic anemia (AIHA) may show temporal shifts in its predominant effector mechanism. Methods We serially assessed clinical course, direct antiglobulin test (DAT) specificity, cold agglutinin activity, complement markers, marrow findings, and immunofixation after rituximab response. Results During winter relapse,
Naru Tomigaki +12 more
wiley +1 more source
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni +4 more
wiley +1 more source
INTERNATIONAL EXPERIENCE WITH 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE
The article is devoted to one of the serious problems of the today's medicine — pneumococcal infection. The authors show its importance for public health in terms of its influence upon infant and child mortality and in validization.
David G. McIntosh
doaj +2 more sources
Progress towards meningitis prevention in the conjugate vaccines era
Acute bacterial meningitis is an important cause of morbidity and mortality among children less than five years old. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis are the most important agents of bacterial meningitis in ...
Cristina Aparecida Borges Laval +4 more
doaj +1 more source
Complement Factor H‐Based Therapeutics: A Comprehensive Overview
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers +2 more
wiley +1 more source
The purpose of the study is to analyze morbidity and to determine etiology of community-acquired pneumonia of conscripts, to examine the epidemiological effectiveness of pneumococcal conjugate and non-conjugate polysaccharide vaccines for the prevention ...
P. V. Kulikov +7 more
doaj +1 more source
ABSTRACT Background and Aim Pneumonia contributes substantially to the childhood mortality burden in low and middle‐income countries (LMICs). Reported predictors of mortality in childhood pneumonia in LMIC are varied. This study aimed to describe predictors of mortality among children with pneumonia in a tertiary hospital in Ghana.
Sandra Kwarteng Owusu +17 more
wiley +1 more source
Protein conjugate pneumococcal vaccines.
BMJ
Spoulou, V. +2 more
openaire +2 more sources

